If you like The Simpsons but are ready for the next step, you'll love Family Guy. Plenty of the storylines are cribbed straight from The Simpsons, but you'll forgive them that because they make them their own, primarily through the unbridled use of adult humour and ability to indulge in all the taboo subjects (you name them, incest, paedophilia, bondage, drug addiction, masturbation, murder, attempted murder (including an ex-Beatle, etc).
Family Guy also has re-invented the use of the flash-back, which I must admit is pretty much the whole basis of its humour.
If you are a guy, and are crass, then you'll lap this up. Without a doubt.