All guns are far more limited in their characteristics.
For example Thumper SMG or Combat Rifles from Hyperion could replace many Sniper Rifles, while S&S Sniper Rifles could double as Combat Rifle.
Useful Gun variety in BL2 feels to be roughly 50% of BL1.
BL2 overuses good punch lines. When Zed explains continuously how he doesn't have a med. degree or Claptrap with his annoying songs. Those become really annoying after a few hours. Tiny Tina saved most of the weird humor I so enjoyed in BL1, without her it'd feel rather dull (not to say dumbed down).
It still has enough guns and humor left also the new classes are fun, but overall it leaves me feeling like something is missing.