How much you would enjoy this really depends on what you want from a novel. If you enjoy literary fiction, constructed almost as much as an art form as a story then this could appeal. The story, about the life and death of an alcoholic and his drug addicted,homeless associates, is delivered in a disjointed, stream of consciousness style, with unfinished sentences, unidentified narrators, verbal tics, and frequent swearing, all of which serve to capture and create the atmosphere of broken lives.
The writing is excellent, and does bring into focus the tragic lives and broken dreams which can lead to decline and life on the street and the consequences of such a life. This is done with empathy, and indeed respect for people as people, even on the very margins of society. It is this empathy for the marginalised and ruined lives of too many who have fallen out of society and cannot find a way back, which is the real strength of this book.
However, it is unremittingly grim throughout - there is not the slightest hint of a happy ending - and many of the scenes are graphic and horrible. I guess that is the point - as a reflection of destroyed lives, only lightened by the drugs which pull the characters down and down, it is excellent,but never enjoyable, reading.