Nero Burning ROM is the standard in DVD burning, and will be the reason most people buy this. I've been happily using the main Nero Burning ROM application for years, and never had any issues.
You now also get a lot of other applications, making this a `multimedia suite'. Some of the additions (such as the ability to convert your mp3s to other formats suitable for mobile phones) are cool, but be wary of installing everything. The Nero extras are notorious for breaking games and pro multimedia applications. One issue for me was that Nero broke the game X3 (no videos play until you uninstall certain Nero codecs). Some Adobe applications also seem to have to fight to regain control of common file types.
If you want just a CD/DVD burner that makes use of the latest burning hardware, can burn the latest ISOs, plus one or two nice music file format converters, then this is a good package *as long as you don't install all the Movie players, music players, and all the other things that your operating system can already do*.
I know why Nero do this: it's a marketing ploy to make it look like you are getting more for your money (especially when Nero comes free with many computers: just go to PC world and you will see all the Nero extras listed as if they were separate applications, giving you a list as long as your arm!).
If like me though, you are serious about your data, stick to installing Nero burning ROM only, and use it for burning data to media. Leave your operating system's default DVD player as the multimedia application of choice and use Adobe Bridge or something similar for your media asset management.