- Hardcover: 1152 pages
- Publisher: W.H.Freeman & Co Ltd; 5th Revised edition edition (18 Aug. 2003)
- Language: English
- ISBN-10: 0716743663
- ISBN-13: 978-0716743668
- Product Dimensions: 22.2 x 4 x 28 cm
- Average Customer Review: 4.2 out of 5 stars See all reviews (11 customer reviews)
- Amazon Bestsellers Rank: 101,092 in Books (See Top 100 in Books)
- See Complete Table of Contents
Molecular Cell Biology Hardcover – 18 Aug 2003
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From the Publisher
Review in the Times Higher 14th April 2000
The life processes brought to life on CD-Rom
"Biologists, from developmental geneticists to ecologists, are faced with the challenge of explaining complex phenomena at mechanistic levels. An essential first step is a solid grounding in biochemistry and molecular genetics. Principles of Biochemistry has always been a favourite of mine, and this third edition is stunning. It is as strong as ever in fundamental aspects of the subject, but it also includes many recent developments. Among the most significant are new chapters on protein structure and function, a revision of oxidative phosphorylation, and descriptions of the major experimental methods and technologies, including NMR, MS and Selex, Also in this edition is a new chapter on signal transduction, which covers one of the most exciting fields in biochemistry.
But what really clinches this text for me is the vitality that bursts from the accompanying CD-Rom. Biochemistry is the study of dynamic cellular processes. To observe the mechanism of translation, DNA sequencing or the infection of a host cell by a single-stranded RNA genome of a retrovirus, while listening to an informative commentary, brings the subject vividly and clearly to life. In addition to superb video clips, the CD-Rom contains a wealth of animations, electron micrographs and chemical structures. Impressive in the latter is the use of a wide variety of molecular representations; there is even a section showing biologically significant molecules in rotatable format.
Of all the sub-disciplines of biology that have benefited from advances in biochemistry, none has done more so than cell biology. Over recent years many of the mysteries of cellular processes, including the trafficking of organelles and spatio-temporal dynamics of specific enzymes, have been unveiled as a result of advances in the technology of fluorescent and luminescent biomolecules. Arguably the most significant of these "reporters" is the green fluorescent protein. The ability to couple transcription or translation of specific proteins to this wondrous reporter means that, with the aid of a confocal microscope, cellular processes can be observed in living cells, in real time. It is truly remarkable.
Molecular Cell Biology, now in its fourth edition, captures much of the excitement of this field as well as providing readers with a broad and sound understanding of the basic principles. Like Principles of Biochemistry, Molecular Cell Biology is accompanied by a variety of teaching aids, and by a similarly superb CD-Rom with animations of complex mechanisms, videos of cell processes and interactive tutorials. The book is up to date and incorporates advances in whole genome sequencing and the challenges these massive data sets present for bio-informatics, plus the latest in functional genomics and micro-arrays. Also worthy of note is the attention drawn to medical and biotechnological implications of many of the cellular processes described in the book.
For me, both these texts set a new level for undergraduate textbooks that I hope all future introductory texts will aspire to. Texts as good as these should change the way biology is taught. Rather than making the lecturer redundant, they provide opportunities for new and innovative approaches to teaching.
Paul Rainey is Lecturer in Microbiology, University of Oxford --This text refers to an alternate Hardcover edition.
About the Author
HARVEY LODISH is Professor of Biology at the Massachusetts Institute of Technology and Member of the Whitehead Institute for Biomedical Research. - ARNOLD BERK is a world-famous Virologist at the University of California, Los Angeles. - PAUL MATSUDAIRA is a Member of the Whitehead Institute for Biomedical Research, Professor of Biology and Bioengineering, Massachusetts Institute of Technology, and Director of the WI/MIT BioImaging Center. - CHRIS A. KAISER is Professor of Biology and teaches genetics at the Massachusetts Institute of Technology. - MONTY KRIEGER is the Thomas D. & Virginia W. Cabot Professor in the Department of Biology at Massachusetts Institute of Technology. - MATTHEW P. SCOTT is a member of the National Academy of Sciences and teaches Developmental and Disease Mechanisms to medical students, and Developmental Biology to graduate students at Stanford University. - LAWRENCE ZIPURSKY is a Professor of Biological Chemistry and an Investigator of the Howard Hughes Medical Institute in the School of Medicine at the University of California, Los Angeles. - JAMES DARNELL is a member of the National Academy of Sciences, Vincent - Astor Professor and Head of the Molecular Cell Biology Laboratory, The Rockefeller University.
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I haven't yet looked at this book in any great detail, but overall it looks very good and will help me with my advanced level studies at level 4, as I'm currently studying HNC... Read morePublished on 6 Dec. 2011 by Gemma pc
Well, I received my book fairly quickly and the quality of the book was not too bad. It wasn't worn out; no annotations or drawings of a previous owner inside the book. Read morePublished on 14 Mar. 2011 by Simon
I am very impressed with the rapid delivery service. I ordered this book on Wednesday afternoon and received the book today (Friday). Read morePublished on 1 Oct. 2010 by T.S.S