Introduction to Bioinformatics Paperback – 10 Mar 2005
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"An excellent beginner's guide to bioinformatics" Amazon.co.uk, May 2002 "Introduction to Bioinformatics is a firstrate response to these demands and provides lucid and well-written explanations of how and why to perform bioinformatic analyses. Arthur Lesk clearly explains the underlying logic of sequence analyses and illustrates what algorithms do, often by use of helpful analogies to everyday life" Times Higher Education Supplement, April 2003 --This text refers to an out of print or unavailable edition of this title.
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Top Customer Reviews
Advanced undergraduate students tackling bioinformatics for the first time, or research students whose experience of bioinformatics is limited to the odd BLAST search and surfing through genomes, will find this book a must have. You will wonder how you ever got by without it.
The book covers all of the major topics in bioinformatics, and touches on several of the minor ones. There are 5 long chapters:
Chapter 1 Introduction: introduces the basics of the field, describing the basics of data archiving, the WWW, computers and computer programming, biological classification and nomenclature, phylogenetic relationships and use of sequences, PSI-BLAST, and protein structure.
Chapter 2 Genome organization and evolution: genomics and proteomics, methods of genetic information transmission, genes and genomes, SNPs, genome evolution.
Chapter 3 Archives and information retrieval: this contains a detailed discussion of various databases and how to interact with them.
Chapter 4 Alignments and phylogenetic trees: this vast majority of this chapter covers many aspects of the important area of sequence alignment, including BLAST and HMMs. Then it has short sections on phylogeny and phylogenetic trees, again covering the basics.
Chapter 5 Protein structure and drug discovery: this starts with protein folding, and deals with hydrophobicity, structural alignments, DALI, and then evolution, classification and prediction of protein structures and function. Finally it touches on drug discovery in this context.Read more ›
Most Recent Customer Reviews
Not an actual introduction on the subject, assumes quite a lot of biology background, but an informative book if you can plow through it.Published 20 months ago by Wizzor
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