I found it enlightening to review mental illness in terms of how biological systems and the autoimmune condition of the individual impact upon them. Of particular interest was the health of the Mother during the first trimester of pregnancy and how influenza in the Mother during this period can increase the incidence of the named conditions in the child and the outcome of Schizophrenia in later teenage years. Toxoplasmosis is also implicated as a precursor to such illnesses. It is not clear whether childhood infection with Toxoplasmosis-gondii in young life during or after birth can increase the onset of Schizophrenia in late teenage years. What I think is missing is how we can relate immune conditions to the negative aspects of Schizophrenia. For example in obsessions that relate to specific recurrent themes such as in Paranoia, where individuals can fear someone is watching them. Can we explain these more abstract features by biological precondition? Are these aspects more likely to be explained by common elements in the environment such as poverty or parenting before condition by unwell individuals?