• RRP: £9.99
  • You Save: £2.00 (20%)
FREE Delivery in the UK on orders with at least £10 of books.
In stock.
Dispatched from and sold by Amazon. Gift-wrap available.
Quantity:1
The Epigenetics Revolutio... has been added to your Basket
+ £2.80 UK delivery
Used: Like New | Details
Sold by ShineWood
Condition: Used: Like New
Comment: Sorry, Christmas Delivery not possible Now
Have one to sell?
Flip to back Flip to front
Listen Playing... Paused   You're listening to a sample of the Audible audio edition.
Learn more
See all 3 images

The Epigenetics Revolution: How Modern Biology is Rewriting Our Understanding of Genetics, Disease and Inheritance Paperback – 1 Mar 2012

4.6 out of 5 stars 157 customer reviews

See all formats and editions Hide other formats and editions
Amazon Price
New from Used from
Kindle Edition
"Please retry"
Paperback
"Please retry"
£7.99
£2.49 £3.23
Note: This item is eligible for click and collect. Details
Pick up your parcel at a time and place that suits you.
  • Choose from over 13,000 locations across the UK
  • Prime members get unlimited deliveries at no additional cost
How to order to an Amazon Pickup Location?
  1. Find your preferred location and add it to your address book
  2. Dispatch to this address when you check out
Learn more
£7.99 FREE Delivery in the UK on orders with at least £10 of books. In stock. Dispatched from and sold by Amazon. Gift-wrap available.
click to open popover

Special Offers and Product Promotions


Frequently Bought Together

  • The Epigenetics Revolution: How Modern Biology is Rewriting Our Understanding of Genetics, Disease and Inheritance
  • +
  • Junk DNA: A Journey Through the Dark Matter of the Genome
  • +
  • Power, Sex, Suicide: Mitochondria and the meaning of life
Total price: £27.95
Buy the selected items together

Enter your mobile number below and we'll send you a link to download the free Kindle App. Then you can start reading Kindle books on your smartphone, tablet, or computer - no Kindle device required.
Getting the download link through email is temporarily not available. Please check back later.

  • Apple
  • Android
  • Windows Phone

To get the free app, enter your mobile phone number.




Product details

  • Paperback: 352 pages
  • Publisher: Icon Books; Reprint edition (1 Mar. 2012)
  • Language: English
  • ISBN-10: 1848313470
  • ISBN-13: 978-1848313477
  • Product Dimensions: 12.9 x 3 x 19.8 cm
  • Average Customer Review: 4.6 out of 5 stars  See all reviews (157 customer reviews)
  • Amazon Bestsellers Rank: 4,551 in Books (See Top 100 in Books)

Product Description

Review

'A book that would have had Darwin swooning - anyone seriously interested in who we are and how we function should read this book.' -- Guardian 'Nessa Carey takes us on a lively and up-to-date tour of what's known about epigenetic mechanisms and their implications for ageing and cancer.' -- BBC Focus '[A] splendidly clear explanation' -- Colin Berry The Oldie 'Fascinating stuff.' -- Bookseller 'A hugely compelling explanation of the very latest from the frontline of modern biology ... The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years.' -- Waterstones 'This is a readable book that applies scientific theory to the everyday world.' -- Bookseller 'Her book combines an easy style with a textbook's thoroughness.' -- Nature 'Sees DNA as a film script, with plenty of room for interpretation and retakes. Carey's experience of the biotechnology industry shows in her concluding remarks on the pros and cons of our growing understanding of epigenetics for drug discovery, and on understanding the impact of diet and environment on disease.' -- Nature 'An exhilarating exploration of an exciting new field, and a good gift for a bright biology student looking for a career choice.' -- Kirkus Review

Review

'A book that would have had Darwin swooning - anyone seriously interested in who we are and how we function should read this book.' (Guardian)

'Nessa Carey takes us on a lively and up-to-date tour of what's known about epigenetic mechanisms and their implications for ageing and cancer.' (BBC Focus)

'[A] splendidly clear explanation' (Colin Berry The Oldie)

‘Fascinating stuff.’ (Bookseller)

‘A hugely compelling explanation of the very latest from the frontline of modern biology … The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years.’ (Waterstones)

‘This is a readable book that applies scientific theory to the everyday world.’ (Bookseller)

'Her book combines an easy style with a textbook’s thoroughness.’ (Nature)

'Sees DNA as a film script, with plenty of room for interpretation and retakes. Carey’s experience of the biotechnology industry shows in her concluding remarks on the pros and cons of our growing understanding of epigenetics for drug discovery, and on understanding the impact of diet and environment on disease.’ (Nature)

'An exhilarating exploration of an exciting new field, and a good gift for a bright biology student looking for a career choice.' (Kirkus Review)

See all Product Description

Customer Reviews

Top Customer Reviews

By D. Jones #1 HALL OF FAMETOP 500 REVIEWER on 30 Dec. 2011
Format: Kindle Edition Verified Purchase
Before I read this book my understanding of genetics was quite naive, I thought DNA made proteins, and if there are mutations in the DNA code then that leads to trouble, such as cancer. But only 2% of the human genome makes protein - what is the other 98% for?

Also consider this: A caterpillar that becomes a butterfly has exactly the same DNA - so why do they look so different?

The answer is 'epigenetics'. Whenever two genetically identical individuals are non-identical in some way we can measure, this is called epigenetics. This also includes an individual at different point in their life. For example why does horrendous abuse as a child often lead to problems later in life - is it psychological or is it embedded in the very genes of the person?

In the following sentence, before I read this book, I mostly understood the word 'within'.

"Histone Acetylation and DNA methylation within a CpG motif in the promoter region mediates gene expression ...."

By half way through this book I understood what this meant.

The author never hides the gritty details from the reader unlike many patronising popular science books that shy away from the scientific detail in case the reader finds it too difficult. She takes you step by step through the main details of epigenetics and the technical language used. It is not difficult, but you do have to take it slowly to digest the information.

To make the subject a bit lighter, the book is dotted with dry humour and pithy literary quotes.

Epigenetics is such a new field that many of the key players are still alive and working away in their laboratories and earning Nobel prizes along the way. She introduces you to some of the leading scientists and the contributions they are making.
Read more ›
Comment 106 people found this helpful. Was this review helpful to you? Yes No Sending feedback...
Thank you for your feedback.
Sorry, we failed to record your vote. Please try again
Report abuse
Format: Hardcover Verified Purchase
What a fabulous book! I couldn't put it down - best page turner I've read for years. Nessa Carey hits just the right note - beautifully clear and pitched at just the right level. She walks you gently through the science, building it up layer by layer, constantly reminding you of the basic facts without making you feel an idiot. All the history of epigenetics, right up to the most current research is covered, with a competent and knowledgable guiding hand. This book makes you think and question everything and it delivers answers to the most intriguing questions. Not only that but it was laced with humour and literary quotes that made reading it a delight. Hats off to Nessa! (Although everything is explained, I would warn readers that a basic knowledge of genetics would be an advantage.)
Comment 61 people found this helpful. Was this review helpful to you? Yes No Sending feedback...
Thank you for your feedback.
Sorry, we failed to record your vote. Please try again
Report abuse
Format: Hardcover Verified Purchase
The promises of the widely hailed genomic revolution did not materialise.The mapping and sequencing of the human genome failed to set in motion great medical breakthroughs because it could only produce a map of the assembly software.It did't explain how it functioned with only 2% of the genome coding for proteins.The DNA blueprint is certainly a starting point but it isn't a sufficient explanation for the complexity of life.It is a script open to multiple interpretations rather than an unchanging mould.

Epigenetics is the new discipline that is revolutionising biology.It has found in Nessa Carey a most engaging and lucid exponent.She writes in a clear non patronising manner using interesting and witty analogies to bring to life a lot of dry biochemical or genetic concepts.Barely a page passes without a new morsel of knowledge is offered with enthusiasm.
Epigenetics describes the set of modifications to our genetic material that changes the ways the genes are switched on or off without altering the genome.Epigenetic modification doesn't change the sequence of a gene but it alters how and when the gene is expressed. It explains how two organisms can be genetically identical yet phenotypically variable, examples identical twins divergence,queen bees and worker bees,catterpillar and butterfly.

The Epigenome is the missing link between nature and nurture as it reflects environmental differences. Epigenetic modifications are heritable in the short term but do not involve mutation of the DNA . It is the mechanism behind transgenerational Lamarckian inheritance ,for instance poor food availability during crucial gestational development may lead to later pathological consequences visiting two successive generations.
Read more ›
Comment 68 people found this helpful. Was this review helpful to you? Yes No Sending feedback...
Thank you for your feedback.
Sorry, we failed to record your vote. Please try again
Report abuse
Format: Kindle Edition Verified Purchase
Word of warning - I may gush! I'm no biologist, but Nessa Carey manages to make epigenetics clear and incredibly interesting to me. This is not an easy read, in that it requires one to think and occasionally to do a little mental gymnastics to get one's head around the concepts she introduces, but nevertheless it's the kind of book that can be gulped down in large servings because Carey is skilled at explaining these high-falutin' concepts so well.

The topics range from inherited traits to cloning and back again, and I found even the descriptions of how certain experiments were undertaken were such that they read incredibly well. This is a book that could havebeen dry as dust, but it's not.

I think probably one where the time taken to read the sample is well spent - I'm sure some people just won't find this that interesting - but if you are at all interested in science, biology, DNA, and the mystery of how things are and aren't passed on, then this is a must read. Absorbing, educational, and downright fascinating. Brilliant.
Comment 30 people found this helpful. Was this review helpful to you? Yes No Sending feedback...
Thank you for your feedback.
Sorry, we failed to record your vote. Please try again
Report abuse

Most Recent Customer Reviews



Feedback