The Epigenetics Revolution: How Modern Biology is Rewriting Our Understanding of Genetics, Disease and Inheritance Paperback – 1 Mar 2012
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'A book that would have had Darwin swooning - anyone seriously interested in who we are and how we function should read this book.' -- Guardian 'Nessa Carey takes us on a lively and up-to-date tour of what's known about epigenetic mechanisms and their implications for ageing and cancer.' -- BBC Focus '[A] splendidly clear explanation' -- Colin Berry The Oldie 'Fascinating stuff.' -- Bookseller 'A hugely compelling explanation of the very latest from the frontline of modern biology ... The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years.' -- Waterstones 'This is a readable book that applies scientific theory to the everyday world.' -- Bookseller 'Her book combines an easy style with a textbook's thoroughness.' -- Nature 'Sees DNA as a film script, with plenty of room for interpretation and retakes. Carey's experience of the biotechnology industry shows in her concluding remarks on the pros and cons of our growing understanding of epigenetics for drug discovery, and on understanding the impact of diet and environment on disease.' -- Nature 'An exhilarating exploration of an exciting new field, and a good gift for a bright biology student looking for a career choice.' -- Kirkus Review
'A book that would have had Darwin swooning - anyone seriously interested in who we are and how we function should read this book.' (Guardian)
'Nessa Carey takes us on a lively and up-to-date tour of what's known about epigenetic mechanisms and their implications for ageing and cancer.' (BBC Focus)
'[A] splendidly clear explanation' (Colin Berry The Oldie)
‘Fascinating stuff.’ (Bookseller)
‘A hugely compelling explanation of the very latest from the frontline of modern biology … The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years.’ (Waterstones)
‘This is a readable book that applies scientific theory to the everyday world.’ (Bookseller)
'Her book combines an easy style with a textbook’s thoroughness.’ (Nature)
'Sees DNA as a film script, with plenty of room for interpretation and retakes. Carey’s experience of the biotechnology industry shows in her concluding remarks on the pros and cons of our growing understanding of epigenetics for drug discovery, and on understanding the impact of diet and environment on disease.’ (Nature)
'An exhilarating exploration of an exciting new field, and a good gift for a bright biology student looking for a career choice.' (Kirkus Review)
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Top Customer Reviews
Also consider this: A caterpillar that becomes a butterfly has exactly the same DNA - so why do they look so different?
The answer is 'epigenetics'. Whenever two genetically identical individuals are non-identical in some way we can measure, this is called epigenetics. This also includes an individual at different point in their life. For example why does horrendous abuse as a child often lead to problems later in life - is it psychological or is it embedded in the very genes of the person?
In the following sentence, before I read this book, I mostly understood the word 'within'.
"Histone Acetylation and DNA methylation within a CpG motif in the promoter region mediates gene expression ...."
By half way through this book I understood what this meant.
The author never hides the gritty details from the reader unlike many patronising popular science books that shy away from the scientific detail in case the reader finds it too difficult. She takes you step by step through the main details of epigenetics and the technical language used. It is not difficult, but you do have to take it slowly to digest the information.
To make the subject a bit lighter, the book is dotted with dry humour and pithy literary quotes.
Epigenetics is such a new field that many of the key players are still alive and working away in their laboratories and earning Nobel prizes along the way. She introduces you to some of the leading scientists and the contributions they are making.Read more ›
Epigenetics is the new discipline that is revolutionising biology.It has found in Nessa Carey a most engaging and lucid exponent.She writes in a clear non patronising manner using interesting and witty analogies to bring to life a lot of dry biochemical or genetic concepts.Barely a page passes without a new morsel of knowledge is offered with enthusiasm.
Epigenetics describes the set of modifications to our genetic material that changes the ways the genes are switched on or off without altering the genome.Epigenetic modification doesn't change the sequence of a gene but it alters how and when the gene is expressed. It explains how two organisms can be genetically identical yet phenotypically variable, examples identical twins divergence,queen bees and worker bees,catterpillar and butterfly.
The Epigenome is the missing link between nature and nurture as it reflects environmental differences. Epigenetic modifications are heritable in the short term but do not involve mutation of the DNA . It is the mechanism behind transgenerational Lamarckian inheritance ,for instance poor food availability during crucial gestational development may lead to later pathological consequences visiting two successive generations.Read more ›
The topics range from inherited traits to cloning and back again, and I found even the descriptions of how certain experiments were undertaken were such that they read incredibly well. This is a book that could havebeen dry as dust, but it's not.
I think probably one where the time taken to read the sample is well spent - I'm sure some people just won't find this that interesting - but if you are at all interested in science, biology, DNA, and the mystery of how things are and aren't passed on, then this is a must read. Absorbing, educational, and downright fascinating. Brilliant.
Most Recent Customer Reviews
The epigenetics revolution is an okay book in terms of requiring general knowledge, but it didn't fulfil what I was after. Read morePublished 3 days ago by Sketcha
Scientists do not always prove to be the best of writers. Nessa Carey is both and writes so that science becomes completely understandable. Read morePublished 22 days ago by Mr. R. A. Penney
Some of the science in this book would at first glance look incomprehensible if it weren't for the amazingly clear narrative text. Read morePublished 2 months ago by K. Law
I enjoy most science books but found this author's style a bit hard to read.Published 3 months ago by Amazon Customer
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