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Blood Viscosity Factors: The Missing Dimension in Medicine Perfect Paperback – 1 Apr 2008
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"Blood Viscosity Factors" brings together a series of essays on the impact of various abnormalities on blood viscosity factors. It contains several hundred references to already published work in the field. Beginning with the finding that red blood cells proliferate in shape and are not just one toroidally shaped horde, the work offers unique insights into the role of ageing and disease. The work of Dr Simpson corrects the record and offers tantalising possibilities for the future. One result of the move to targeted and commercial research has been to stunt the growth of whole fields of inquiry in favour of more convenient or competitive ways of looking at a situation. The real puzzle is that the work has been done and a substantial body of peer reviewed publications attest to the quality and depth of the findings. The book is of interest to those readers who prefer a more holistic view of science and the world, than is currently offered by the standard texts.
About the Author
Dr. Leslie Simpson graduated from the University of Otago in New Zealand in Zoology and later was awarded a Ph.D. in Experimental Pathology. After a variety of employment including Military Service, he became active in research with the Pathology Department of the University of Otago, Medical School. He served for seven years in the World Health Organization. Initial studies of the difference between healthy subjects and the general population led to a focus on the impact of blood viscosity on ageing and other aspects of health. This in turn led to the recognition that certain abnormalities were characterized by a loss of deformability and filterability of blood cells.
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13 November 2011
Format: Perfect PaperbackVerified Purchase
This fascinating and important work is about blood rheology - the physical properties of our red blood cells. Dr. Simpson has published 120 research papers, studying changes in the shape-populations of red blood cells and how these affect the delivery of oxygen and removal of waste products in tissues and organs affected in a range of chronic illnesses, including ME, MS, and diabetes, as well as congential conditions, Down's Syndrome and Huntingdon's. Normal red blood cells are biconcave discocytes, round, dimpled on both sides, and able to deform (curl up!) sufficiently to flow into the tiny capillaries on which our muscles, brain, endocrine system and all other tissues and organs depend for their supply of oxygen. Red blood cell populations are sensitive to changes in their environment, and in the conditions mentioned above, will become dominated by a high percentage of other, irregular shapes, visible in micrographs of immediately fixed blood samples. These are inflexible (poorly deformable)and cannot traverse the capillaries, creating the problems we see in these illnesses. 4 gm per day of genuine EPO, 6 gm a day of fish oil, pentoxyfilline (Trental), or vitamin B12 administered as hydroxocobalamin will improve blood viscosity and improve the well-being of a significant proportion of sufferers from the above conditions. In particular, pentoxyfilline prevented the occurrence of secondary problems in diabetics in a four year study. People with ME also can experience marked improvements. But medical literature and medical training completely ignore the work of haemorheologists, up to now.