Enter your mobile number below and we'll send you a link to download the free Kindle App. Then you can start reading Kindle books on your smartphone, tablet, or computer - no Kindle device required.
Getting the download link through email is temporarily not available. Please check back later.

  • Apple
  • Android
  • Windows Phone
  • Android

To get the free app, enter your mobile phone number.

Kindle Price: £95.00

Save £15.00 (14%)

includes VAT*
* Unlike print books, digital books are subject to VAT.

These promotions will be applied to this item:

Some promotions may be combined; others are not eligible to be combined with other offers. For details, please see the Terms & Conditions associated with these promotions.

Deliver to your Kindle or other device

Deliver to your Kindle or other device

Kindle App Ad

Bioisosteres in Medicinal Chemistry, Volume 54 (Methods and Principles in Medicinal Chemistry) Kindle Edition


See all formats and editions Hide other formats and editions
Amazon Price
New from Used from
Kindle Edition
"Please retry"
£95.00

Length: 256 pages

Kindle Books from 99p
Load up your Kindle library before your next holiday -- browse over 500 Kindle Books on sale from 99p until 31 August, 2016. Shop now

Product Description

Review

In all, I believe this book is a musthave handbook on bioisosteres. It is highly valuable both as a text book for graduate students and as a book of reference for the medicinal chemist working in the industry as well as in an academic setting.   (ChemMedChem, 1 July 2013)

From the Back Cover

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism.
As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development.

The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered,
while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part
covers the four key methodologies for bioisostere identification and replacement: physicochemical properties, topology, shape, and overlays of
protein–ligand crystal structures. In the final part, several real–world examples of bioisosterism in drug discovery projects are discussed.

With its detailed descriptions of databases, methods and real–life case studies, this is tailor–made for busy industrial researchers with little time for reading, while remaining easily accessible to novice drug developers due to its systematic structure and introductory section.

Product details

  • Format: Kindle Edition
  • File Size: 3090 KB
  • Print Length: 256 pages
  • Publisher: Wiley-VCH; 1 edition (27 Jun. 2012)
  • Sold by: Amazon Media EU S.à r.l.
  • Language: English
  • ASIN: B00DF3U7FC
  • Text-to-Speech: Enabled
  • X-Ray:
  • Word Wise: Not Enabled
  • Enhanced Typesetting: Not Enabled
  • Average Customer Review: Be the first to review this item
  •  Would you like to give feedback on images or tell us about a lower price?

Customer Reviews

There are no customer reviews yet.
5 star
4 star
3 star
2 star
1 star
click to open popover