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DO NOT BUY if you use WD USB 3 hard drives
on 29 December 2013
More details are available on the Western Digital forums and at goo.gl/yFlA4f. The Fresco Logic USB 3 chips do not work well with devices that don't support link power management (LPM, USB 3 power saving) and unlike the USB 3 chips from Renesas (NEC) and Intel, LPM cannot be disabled on the FL100x or FL1100. There is a solution of sorts on the link I posted above for cards that use the older 2-port chips (using a very old driver that did not have LPM enabled) but this will NOT work for 4-port cards that use the FL1100 like this one. In addition to frequent drive disconnects, I was also getting very bad speeds (~ USB 2 speeds) when copying files between drives connected to the same card.
For the moment, I'd advise any Windows users (I'm not sure what the Mac situation is) that have or plan to get a WD USB drive to get a card that uses the Renesas uPD720201 chip instead. LPM can be easily disabled, and I've had no problems with any devices. Copying between drives connected to the same card is much faster also. You can find 4-port cards that use the uPD720201 here on Amazon, and they're even cheaper than these FL1100 cards too.
I would just add that SpringRain have been very willing to help and offer suggestions and have provided great customer service, this compatibility issue should not be taken as any criticism of them as a seller.