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Customer Discussions > philosophy discussion forum

The Philosophy Of Extended Youth Span: Protocols For Staying Young: Elixers Of Youuth: An Ageless World: Biological Age Control.


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Showing 1-25 of 32 posts in this discussion
Initial post: 6 May 2012 11:33:03 BDT
Last edited by the author on 6 May 2012 11:36:11 BDT
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Posted on 6 May 2012 13:28:41 BDT
gille liath says:
Because you're worth it...

Posted on 6 May 2012 14:04:03 BDT
New study identifies role of large protein fragment in blocking amyloid build-up
April 13, 2012

Plaques made up of abnormal deposits of beta-amyloid protein are a hallmark of Alzheimer's disease. The toxic buildup begins when the beta-secretase enzyme (BACE), working in concert with a partner enzyme, snips a small fragment of amyloid precursor protein (APP) and releases beta-amyloid from the cell membrane of neurons. The beta-amyloid can then gradually clump together to form the well-known plaques that may cause damage to brain cells. Now a new study primarily funded by NIA appearing in the April 10, 2012, issue of Nature Communications has revealed a previously unknown interaction between BACE and a large APP fragment called sAPPalpha that blocked the buildup of plaques in mice. The novel findings may lead to new therapeutic targets for Alzheimer's researchers.

Scientists at the University of South Florida, Tampa, discovered that the sAPPalpha fragment, which is released from neurons at synapses (the tiny gap between neurons across which neurotransmitters travel during communication), interfered with BACE activities in mouse models with Alzheimer's pathology. Increased levels of sAPPalpha blocked the ability of BACE to snip the APP protein and reduced levels of amyloid plaque buildup in the brains of the mice. Because lower than normal sAPPalpha levels are often found in people with Alzheimer's, restoring or enhancing these levels may be one avenue to investigate for slowing onset or progression of the disorder.

Reference: Obregon D, et al. Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation. Nature Communications. 2012 Apr 10;3:777. doi: 10.1038/ncomms1781.

Posted on 6 May 2012 15:23:45 BDT
Is this in your opinion then to be speculatively associated on any at all level with the proposition, from whichever lab, that protein shakes should be of some considerable benefit to the over fifties? The more obvious and speculated for anabolic benefits might also be discussed at some point. Whilst your debate hopefully continues, at my next visit I shall be offering up for your comments products which from my understanding of the research as it presently stands are very good bets for youth extension.
Thank you for joining this thread.

In reply to an earlier post on 6 May 2012 19:36:58 BDT
gille liath says:
You're welcome!

In reply to an earlier post on 7 May 2012 05:54:19 BDT
Dear Discodavey.....resveratrol seems good....

Posted on 7 May 2012 10:52:53 BDT
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Posted on 7 May 2012 12:24:21 BDT
Serotonin??????.....not a product....also NADH....no such thing as natural progesterone...

Posted on 7 May 2012 12:39:53 BDT
All these potions are snake oil, until you can regrow Telomeres they're just straws to grasp at.

In reply to an earlier post on 7 May 2012 13:46:43 BDT
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Posted on 7 May 2012 15:28:57 BDT
Last edited by the author on 7 May 2012 15:37:17 BDT
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In reply to an earlier post on 7 May 2012 15:34:31 BDT
There is no evidence creatine increases muscle mass in people not engaged in progressive resistance training...serotonin is a neuro transmitter very different from DHEA...

Posted on 7 May 2012 15:47:28 BDT
Last edited by the author on 7 May 2012 16:04:55 BDT
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Posted on 7 May 2012 17:10:55 BDT
Last edited by the author on 7 May 2012 17:12:31 BDT
I think there are many benefits to be had from eating tasty nutritious food, apparently it contains vitamins, minerals, protein and suchlike.

In reply to an earlier post on 8 May 2012 09:51:59 BDT
Last edited by the author on 10 May 2012 18:15:55 BDT
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Posted on 9 May 2012 11:08:02 BDT
Last edited by the author on 9 May 2012 11:08:57 BDT
The Truth says:
There's a lot to be said for growing old gracefully.

My nan says that the best years of her life started after she turned 60 - she's now in her late 80s. Why not accept who you are and stop fighting nature, or you could miss out on the best years of your life... and all for nothing - because I have news for you. You will at some point die.

Plus - and I'm not being nasty here - but I looked at your website, and judging from the photos on there, whatever you're doing to combat the ageing process isn't working. Just saying. In fact you look worn out and unhealthy in a lot of those pictures.

My advice best advice if you want to stay looking young and feeling healthy is this: ease up on the partying, exercise, eat well and be happy with who your are and where you're at in life.

There's a saying: you often meet your destiny on the path you take to avoid it.

Posted on 9 May 2012 18:26:52 BDT
Last edited by the author on 10 May 2012 18:27:42 BDT
The Truth
It`s of course most likely the case you`d claim I looked unhealthy by way those pictures no matter what I looked like, and all the more especially because I`m older than the other clubbers. They had however made me their very first vitality celebrity, a leading nightclub, and at an over eighteens, not twenty fives! My age was fifty four. One obviously looks rather tired and wornout however, at two in the morning, having worked hard all day, and now just danced half the night. Also, at the time of creating this site the plan was that I should look as old and grey as possible, for the site concerns social age prejudice over friendships, and you can follow me on this subject right here, linked back to my site.

Your quite right however, clubbing and ageing usually go hand in hand! However, that was where I was at up until three years ago, (I never drank or did any drugs however, nor have I ever smoked) and I was happy with it, as much so as any clubbing teen. I`m now preoccupied with establishing G.W.Records in physical speed and endurance. As for your saying, a very valid one, it`s also the case that the path one follows in avoiding one`s otherwise destiny, and obviously therefore one eventually finishing in death, may be the right and at the same time more natural path for that individual.

We think we know something about an individual on account of how long we are told that person has been alive, but truth is that`s wrong thinking, and in my opinion is a part of what is in fact actually biult into an accelerated ageing condition - We may be at least in some part socially predisposed to age faster than is argueably natural.

The best years of one`s life may be more likely to begin at sixty by the route of giving nature a helping hand, you don`t think?? The point I`m making is that we may have discovered a capacity, one of course as yet largely untapped, for somewhat more capacity for ultimate health and vitality than those possessed by our fellow creatures, and here I don`t refer to those of them that live in and arouind towns, he he. This is to say, when it comes to optimal youth span, and freedom from the ailments which generally tend to come with the passage of time. Obviously, the vast majority of us don`t even get as far as optimal nutrition, and again, fairly obviously I think, if one were looking for a problem this is where to be looking first.

Thank you for your comments, but the biological markers for ageing, not a single one of them, are to be discovered anywhere on my website. Suffice to say that young company is not necessarily the killer which it is so often mistakenly claimed to be. Truth is that the slower pace of mediocracy is one of our biggest killers! One of the others can be a mid-life crisis, but to simply maintain a level of physical activity has the best possible outcome.

You come across rather like a girl in her teens or perhaps early twenties, a wise one obviously, he he.

In reply to an earlier post on 9 May 2012 23:20:19 BDT
Last edited by the author on 9 May 2012 23:22:26 BDT
The Truth says:
LOL. Sorry to disappoint DD, but I am in fact a man in his mid 30s...

Fair play then mate, sorry if I judged you in anyway. From what you say in your last post I was way of the mark. Having been in the music biz I've just met a lot of clubber casualties in my time and took you for one of them.

Good luck with the GWRs then and take it easy with the creatine. It can knack your kidneys.

In reply to an earlier post on 10 May 2012 13:57:14 BDT
Last edited by the author on 10 May 2012 18:21:02 BDT
That`s right, we do at some point require to examine which groups may benefit, and the environment for taking each respective product safely. As I currently understand it there is a slightly increased fluid requirement when taking the standard 10 gm dose of creatine. One should be consuming not too much more than this in a single day, and sugars are required for its better absorption. The answer seems to me to be a simple one, that this product should be added to substantial fluid and taken this way, not off a spoon, nor in tablet form. You are right, there are a lot of casualties around clubbing.
Thanks very much for the support.

Posted on 10 May 2012 16:01:16 BDT
Withnail says:
http://www.youtube.com/watch?v=N1KvgtEnABY

Posted on 10 May 2012 18:15:00 BDT
Last edited by the author on 10 May 2012 18:21:28 BDT
No matches! He he!!

Posted on 29 May 2012 20:07:12 BDT
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Posted on 28 Jun 2012 12:21:56 BDT
(Tumbleweed blows slowly past)

Posted on 10 Aug 2012 11:08:53 BDT
Charlieost says:
(A vulture alights on a crumbling roadsign, see's that there are no pickings and takes off again.)

Posted on 12 Aug 2012 11:17:14 BDT
That`s good, but why the brackets??
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Participants:  10
Total posts:  32
Initial post:  6 May 2012
Latest post:  1 Feb 2013

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