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28 of 29 people found the following review helpful:
5.0 out of 5 stars
LORENZO'S OIL...THE ELIXIR OF LIFE..., 17 Nov 2002
This is the true life story of the Odone family, Augusto, Michaela, and Lorenzo, and their battle with Adrenoleukodystrophy (ALD), a disease that attacks the central nervous system by systemically destroying its protective cover, the myelin sheath. It is an extremely rare disease that is transmitted exclusively to males through a gene that is carried by the mother.Augusto, an economist, and Michaela, a linguist, were a well educated, well to do, multi-lingual couple with a little son named Lorenzo who was precocious beyond his years. He spoke English and Italian fluently, as well as the language spoken in the community in Africa in which he spent his very early years. When he returned to the United States at about the age of five, his behavior started to change He came overly aggressive and was given to emotional outbursts. After much angst on the part of the Odones over what could be wrong, they were finally told that their son suffered from ALD, which was the functional equivalent of having their son being given a death sentence, as there was no cure for this degenerative disease. This well educated couple refused to accept the death sentence meted out to their son by the medical establishment. With no medical background, they disregarded conventional medical wisdom and went about trying to find a cure for their son, in a quest so remarkable and so moving, as to inspire absolute awe in the viewer. A more caring or loving set of parents would be hard to find. Lorenzo is surely loved. Together, Augusto and Michaela take on the medical establishment. What they ended up discovering rocked the medical world. To find out just what it was that they specifically did, you will just have to watch the movie. Director George Miller does a masterful job in directing this film, avoiding the obvious sentimental traps and playing the film out in a very straightforward way. The ravages of this disease are fully played out and are not sugarcoated in any way. Nick Nolte gives a bravura performance as Augusto Odone, though his Italian accent needs a little work. He is superb as the father who transfers his emotion to the task of learning biochemistry in order to ascertain just what factors are at the root of his son's disease. His way of dealing with his son's illness is intellectual and methodical. Susan Sarandon is sensational as Michaela Odone, a woman of such strength, resolution, and determination that it would be hard to find another like her. Her pain is palpable, as she sees her son deteriorate, but she refuses to take the path of least resistance where Lorenzo is concerned. In the face of daunting odds, she perseveres with Lorenzo, talking to him, as well as stimulating and challenging him. A notable performance is also given by Kathleen Wilhuite who plays the part of Dierdre Murphy, Michaela's sister and Lorenzo's loving aunt. This is a sensational film that avoids all the maudlin, sentimental traps laid out in the formulaic disease of the week movies one often finds. This is a deftly directed, well acted film, informative and moving. It is a film that will stay with the viewer, long after the credits have rolled off the screen. Bravo!
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