#69 in	Books > Scientific, Technical & Medical > Medicine & Nursing > Medical Sciences A-Z > Diseases & Disorders > HIV-AIDS
#70 in	Books > Science & Nature > Medicine > Diseases & Disorders > Infectious & Contagious Diseases > HIV-AIDS

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Amazon.co.uk Review
The origin of the AIDs epidemic has been one of the major scientific riddles of our time. Edward Hooper's The River is a brilliant piece of scientific journalism that attempts to offer some worthwhile answers and, in doing so, raises some uncomfortable questions. "The biotechnological advances of the last 25 years hold out tantalising promises of human advancement and happiness, but they also confront us potentially with the greatest dangers our species has ever faced." Hooper certainly manages to clear the ground, demolishing a lot of the standard hypotheses on how the AIDs epidemic started. Instead, he produces one that has, at the very least, the merit of being directly falsifiable, however controversial and productive of litigation. In doing so, he raises important questions about the public ethical accountability of scientists, the use of human beings in experiments and the use of animals as the source for vaccines and transplants. If he is right, the attempt in the 1950s to tackle one major epidemic, polio, has inadvertently produced another even greater plague; and even if he is wrong, he has raised some important questions. This is not just a scientific investigation, of course; it is an important human story and Hooper's interviews with many of the scientists involved in tracing the origins of the epidemic are smart and humane. This is a crucial book that no one interested in the issues it raises can afford to ignore. --Roz Kaveney

Product Description
Based on nine years of full-time research by science journalist, Edward Hopper, this text presents an investigation into the origins of AIDS.

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6 of 6 people found the following review helpful:

4.0 out of 5 stars An interesting thoroughly well researched book., 11 Sep 2000

By A Customer

The River is a thoroughly researched and detailed book. It contains a great deal of medical terminology which makes it difficult for the lay person to read. However it is worth persevering with and does provide guidance with over 200 pages of notes. The basic premise of the book is that during the 1950's SIV (simian immunodeficiency virus-prevalent in chimpanzees ) was transferred to humans via experimental polio vaccines resulting in HIV and AIDS. Hooper traces the origin of HIV looking at the first truly authenticated cases and tries to follow a path (The River) back to them and the origin of the transmission. He appears successful in most cases although it is impossible in very early cases as no tissue samples are left (or made available). Perhaps the most interesting parts of the book are in his discussions with the scientists who created the early polio vaccines. As expected they deny that this is a possibility but as the picture builds the finger appears to point evermore in their direction.This is especially clear when it is shown that the creaton of polio vaccines in chimpanzee kidneys was not 100% safe.The genetic origins of HIV show a definite jump from monkey to man occurred. If you have an interest in the origin of HIV and AIDS then this book is definitely worth reading.It is long and can become complicated but the story of HIV/AIDS has never had a simple history.There have been so many theories from so many places that the waters became very muddied. Hooper has helped to clear the waters and has identified the most probable origin of HIV.He has backed it up with thorough research and only time will tell if he is correct.Well worth reading. Stephen Humphries

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5 of 5 people found the following review helpful:

4.0 out of 5 stars A very, veyr important piece of work, 9 Sep 2000

By	laura.hogan@nuigalway.ie (Galway. Ireland) - See all my reviews

This is not a book to be undertaken lightly. Definetly not the sort of thing to read on your two weeks in the sun. Its 50+ chapters need to be read slowly, studied and digested. Hooper's thesis is that the AIDS virus is essentially a human invention. It mutated from the monkey version of HIV (SIV) when monkey kidney tissue was used to make Oral Polio Vaccines in the 50's. These vaccines were extensively tested in central and west Africa, the current epicenter of HIV and the disease spread from there. This is a brilliantly researched piece of work, describing both the history of HIV, AID and OPV research and the authors own journey to the source of the river of AIDS. I have only one grumble and that is the length. It is not an easy read. Hooper would undoubtedly find a much wider audience with a slightly less detailed work. The general reader does not need to know the detail of every OPV trial that took place in the 50s and the core of this work would not be lost for the lack of such detail. Nonetheless, a very important, beautifully written piece of work that will surely find its way to the bookshelf of anyone interested in science or the world around us and man's influence on that world.

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