Metabolic Engineering: Principles and Methodologies (Hardcover)

Product Description
Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes.
Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems.


Key Features
* Demonstrates metabolic engineering in action with numerous examples of pathway modification
* Includes methods for identifying key enzymes in metabolic networks
* Contains a comprehensive review of metabolic biochemistry
* Discusses metabolic regulation at the gene, enzyme, operon, and cell levels
* Explains concepts of stoichiometry, kinetics, and thermodynamics of metabolic pathways
* Minimizes mathematical complexity
* Links to a Web page to communicate updates of the software code and homework problems

About the Author
Gregory Stephanopoulos is a Professor of Chemical Engineering at MIT. He received his B.S. from the National Technical University of Athens, his M.S. from the University of Florida and his Ph.D. from the University of Minnesota, all in Chemical Engineering. Upon graduation, he joined the Chemical Engineering Faculty of the California Institute of Technology, where he served as Assistant and Associate Professor until 1985. In 1985 he was appointed Professor of Chemical Engineering at MIT where he has been ever since.Stephanopoulos' work has appeared in more than 150 publications and 7 patents. He has been recognized with the Dreyfus Foundation Teacher Scholar Award (1982), Excellence in Teaching Award (1984), and Technical Achievement Award of the AIChE (1984). He has been a Presidential Young Investigator and the Chairman of the Food Pharmaceutical & Bioengineering Division of the American Institute of Chemical Engineers (1992). In 1992 he was a Visiting Professor at the International Research Center for Biotechnology at Osaka University and was elected a Founding Fellow of the American Institute for Medical and Biological Engineering. In 1996 he chaired the first Conference on Metabolic Engineering and gave the inaugural Bayer Lecture on Biochemical Engineering at the University of California at Berkeley. He was honored with the FPBE Division Award at AIChE in 1997.

First Sentence
The concept of metabolic pathway manipulation for the purpose of endowing microorganisms with desirable properties is a very old one indeed. Read the first page Browse Sample Pages
Front Cover | Copyright | Table of Contents | Excerpt | Index

Search inside this book:

There are no customer reviews yet.   Create your own review
Video reviews New feature! Amazon now allows customers to upload product video reviews. Use a webcam or video camera to record and upload reviews to Amazon.	Ad feedback

• Books > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Ancillary Services > Biomedical Engineering
• Books > Science & Nature > Biological Sciences > Biological Science > Cell Biology
• Books > Science & Nature > Biological Sciences > Biological Science > Molecular Biology
• Books > Science & Nature > Biological Sciences > Genetics
• Books > Science & Nature > Engineering & Technology > Bioengineering > Biomedical
• Books > Science & Nature > Engineering & Technology > Bioengineering > Biotechnology
• Books > Science & Nature > Engineering & Technology > Chemical > Industrial Chemistry
• Books > Science & Nature > Popular Science > Genetics
• Books > Scientific, Technical & Medical > Biology > Cellular Biology
• Books > Scientific, Technical & Medical > Biology > Genetics > Genomics
• Books > Scientific, Technical & Medical > Engineering > Biomedical Engineering
• Books > Scientific, Technical & Medical > Medicine & Nursing > Basic Medical Science > Biochemistry

• Would you like to update product info or give feedback on images?
• I am the Author, and I want to comment on my book.
• I am the Publisher, and I want to comment on this book.