It will probably work from a technological stand point. Plug stuff in, and a picture will appear. However I would expect that it would not be very nice to use, and to be very clunky. 2560x1600 is a very high res, and if this is planned for gaming i would advised against it. If you just want to use it for a 2nd monitor, or youtube/tv etc, then it might work. But the graphic card (probably integrated on a laptop) will be working very hard, very hot, and other things will be effect its performance. Hope this helps.