Do not allow the subtitle, "The Covert Government Experiment That's Killing Our Soldiers and Why GI's Are Only the First Victims" to turn you off this book. It could be misinterpreted as a new age conspiracy theory-type work, when it is in fact a most seriously-minded piece.
Matsumoto does an immediately fine job of walking the reader through the molecular biology that is requisite to understanding the argument of his book: that US military researchers (biochemists and molecular biologists) began using the oil "squalene" as the main adjuvant to the Anthrax vaccine which was created to immunize US, British, and Canadian military forces prior to the first Gulf War (this was necessary because it was thought Saddam Hussein had a functional Anthrax biological weapon).
The oil squalene has a molecular composition very similar to other lipids (fatty, waxy substances) found naturally in the body; however when squalene is injected as the adjuvant of an Anthrax vaccine, the body begins producing antibodies against squalene -- which the immune system then has difficulty distinguishing from its own naturally-occurring lipids. The result is that the body begins destroying itself, causing severe autoimmune diseases such as Lupus, Multiple Sclerosis, and a host of others.
Extant vaccine stockpiles being very low and almost incompetent to provide protection against Anthrax prior to the first Gulf War, military scientists were charged with producing an "improved" vaccine capable of protecting against multiple, highly virulent strains of the Anthrax bacillus -- with little time in which to do it. This eventually led them to utilize squalene as an adjuvant in their "improved" vaccine (for reasons only they truly know), which then killed or seriously incapacitated many servicepeople with autoimmune diseases for the rest of their lives.
A large portion of Matsumoto-san's book discusses how US military scientists had a corpus of specialist immunological literature at hand that demonstrated these diseases developed in clinical trial, when squalene was injected into guinea pigs and rats (which they then ignored and even denied was valid).
The book then goes on to give many intimate, clinical descriptions of the diseases developed by some of the soldiers after receiving Anthrax vaccine from certain lots. Research conducted by Dr. Pam Asa and Dr. Bob Garry to determine the cause of these diseases is then discussed in some detail, along with the realization that it was the Armed Force's Anthrax vaccine that was causing symptoms commonly referred to as "Gulf War Syndrome."
Matsumoto is to be commended for maintaining a neutral tone throughout the book, which must have been difficult. The examination is most fair; he even does a good job of conveying the anxiety that must have been experienced by the military scientists responsible for producing the "wonder drug" in 10 seconds or less.
His rather skilful writing does not emerge as anti-military, anti-establishment, or even anti-FDA, although any of these positions would be understandable given his experiences. Neither does he spend any time bashing the 'villains' of the story, instead reporting the actions of certain high ranking military officers and doctors and then moving on. Matsumoto-san's narrative is accompanied by copious footnotes, leaving the reader to pass his or her own moral judgements. The voice of the author emerges only when he compassionately describes the suffering of the soldiers who developed these advanced autoimmune diseases as a result of the military-issued Anthrax vaccines they received. Excellent journalism: utilizing a format which strengthens the credibility of his arguments (show and tell, not scream and preech).
One criticism is that Matsumoto-san takes up too much space pursuing his argument in the end-game. The last hundred or so pages were almost all reiteration of the earlier, prerequisite arguments for understanding the main gist of the book; this reiteration could have been dispensed with completely to make the book shorter and more poignant, as well as tighter in focus and organization. The message of the book arguably would have been much sharper if it had ended when Matsumoto reported his last clinical case and then ended the manuscript. Instead I found myself scanning and then skipping large sections of the end of the book to get to the wider-spaced clinical and research details.
Importantly this work does not suffer from the editorial issues that are becoming common in mass-market books today. The grammar, spelling and type editing of the book are very good, with few mistakes observed.
The issue the book introduces is most serious, and Matsumoto-san should be congratulated for having the courage to pursue the research in the face of what amounts to official ridicule. A highly recommended read, especially within the wider context of historical Anthrax epidemiology (the likes of which is touched upon by way of introduction to the present volume within the context of the Sverdlovsk outbreak in the former Soviet Union).
Four stars given for the importance of the subject matter and the skill with which it is conveyed; a shorter, tighter book might have merited five stars. Bravo for a fine effort.