Tuning the Brain
Two paragraphs of this book contain more neurochemical information than two pages of most books. Although I feel uncomfortable with the minimal attention Goldstein pays to detecting and treating the numerous viral, bacterial and fungal infections involved in Chronic Fatigue, Fibromyalgia, Irritable Bowel and Interstitial Cystitis, I feel his understanding of neurochemistry may be unparalleled. I would like to have read more about his experiences with intravenous Vitamin C treatment, which I believe may be the single most effective treatment for these disorders.
His diagnostic concept of quickly reaching the brain, by applying medications via ophthalmic, nasal and sublingual routes appears to have merit, since some of these sensory organs are only removed from the brain by two or three neurosynapses. The dramatically rapid improvements he describes using Naphazoline eyedrops, Nifedipine calcium channel blockers, sublingual Ketamine and other prescription medications are intrigueing.
Unfortunately Abecarnil and some of the other medications he discusses are not available in the United States, while others including Adenosine, with a ten second half life, would be of limited value, for chronic disease treatment.
Tragically, this brilliant, dedicated, devoted, unselfish physician reports he was unable to earn a living, testing and treating these very sick, labor intensive, exhausting patients, who have so many medical problems, requiring intervention after intervention. Health insurers and most patients do not want to pay for the level of care necessary to effectively treat these difficult patients for their numerous medical problems. Unfortunately, some of his patients were very selfish, demanding, manipulative and dishonest.
I recommend reading Betrayal by the Brain, before attempting to digest the incredible wealth of complex biochemical and neurochemical information in Tuning the Brain. I would not be surprised to learn that Dr. Jay Goldstein is awarded a Lasker or Nobel Prize when sufficient scientists succeed in comprehending the information he has written in this incredible book.
I was saddened to learn Dr. Jay Goldstein has retired, but am grateful for the outstanding contributions he has made to our understanding of neurochemistry, chronic pain, fibromyalgia, multiple chemical sensitivity, irritable bowel, interstitial cystitis, insomnia, anxiety, addiction and chronic fatigue treatment.
Steven Sponaugle