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Tuning the Brain: Principles and Practice of Neurosomatic Medicine [Paperback]

Jay Goldstein


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Jay A. Goldstein
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According to a leading CFIDS patient advocate, Tuning the Brain is: "A Lucid, Wonderful, and Wonder-Filled Book crammed with patient-tested secrets based on years of clinical experience. If more physicians had Dr. Goldstein's ability to see and respond to the needs of their patients, the world would not be filled with the distrust for medical practitioners that is so prevalent today. The author was and is years ahead of his time in understanding how the brain functions and has taken neurosomatic medicine to new heights. Both the book and the man can be described in one word: Brilliant."

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Discover effective, outcome-oriented ways to help CFS patients who have endured useless or inappropriate treatments!

From the author: “For many years I have viewed brain function as a system of electrochemical impulses continually flashing through the brain. These neural networks can often be modulated fairly simply by ’tuning’ them. The point I have been trying to make for many years is that this process may be pharmacologically regulated extremely rapidly in a manner which does not yet seem to be recognized by the medical profession.”

In this remarkable volume, Dr. Jay A. Goldstein clearly presents both the theoretical and the practical aspects of his revolutionary approach to treating CFS and other conditions that have often been termed psychosomatic. Dr. Goldstein (author of Chronic Fatigue Syndromes: The Limbic Hypothesis and Betrayal by the Brain: The Neurologic Basis of Chronic Fatigue Syndrome, Fibromyalgia Syndrome, and Related Neural Network Disorders) shows how he achieves results for patients with CFS and a variety of other syndromes in days, rather than months or years.

This well-referenced book answers questions, from the most basic to the most complex, including:
  • What is neurosomatic medicine?
  • How did Dr. Goldstein come to pioneer and practice this specialty?
  • What abnormalities in brain function produce neurosomatic disorders?
  • How can an understanding of these abnormalities help you provide effective treatment?
  • Why do these treatments sometimes work so rapidly?
  • What is receptor profiling, and how does it indicate the type of receptor dysregulation in an individual patient?
In Part I: Inventing Neurosomatic Medicine, Dr. Goldstein describes the remarkable how and why of his life and his development of this new field of medicine, including his clashes with the medical/psychoanalytic establishment. One of the greatest medical innovators of the modern era, Dr. Goldstein has seen over 20,000 CFS patients and has experienced most of the pitfalls that having such a large number of patients entails. He shares his insight on legal issues, such as how to deal with the law and court systems, how to best provide expert testimony, and how to defend against spurious legal actions. In addition, Dr. Goldstein describes how he learned to work effectively outside of the managed care system.

In Part II: Society for Neuroscience Conference Proceedings, the author shares his expertise to bring you experimental results and “pearls of wisdom” relating to neurosomatic medicine from the 28th and 29th Annual Meetings of the Society for Neuroscience—the largest and most important neuroscience conference in the world. Dr. Goldstein sorted through thousands of experiments presented at the conferences to bring you the most relevant findings.

Part III: Pathophysiology and Treatment is essential reading for anyone planning to practice neurosomatic medicine. In this section, richly illustrated with over 70 pages of color figures and diagrams that make complicated concepts clear, Dr. Goldstein shares his knowledge about dozens of the agents he uses to help CFS sufferers and others manage their pain, fatigue, and other symptoms. This is information that simply cannot be found anywhere else, and will prove invaluable to all fledgling neurosomatic practitioners.

This one-of-a-kind volume is thoughtfully put together—from the extensive list of abbreviations near the beginning to the exhaustive references and an appendix with diagnostic criteria, a treatment algorithm, a medication list of treatment options available now or in the near future, and a checklist of CFS symptoms.

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To understand other aspects of my early life please refer to Portnoy's Complaint, by Philip Roth (1969). Read the first page
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Front Cover | Copyright | Table of Contents | Excerpt | Index | Back Cover
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Amazon.com:  3 reviews
25 of 27 people found the following review helpful
Dr. Goldstein's treatment approach was very effective for me 7 April 2004
By Matthew Simon - Published on Amazon.com
Format:Hardcover
I was housebound and often bedridden for 15 years with severe Chronic Fatigue Syndrome. I tried many treatment approaches but nothing had any beneficial effect. I began working with Dr. Goldstein in 2001, following the experimental drug protocol set forth in this book. I was on the meds he prescribed for 3 years. During that time, I gradually recovered. I am now off the meds, working fulltime, and living a normal life. I know this approach does not work for everyone, but it has worked for many people with CFS, and I would recommend giving it serious consideration. Dr. Goldstein's hypothesis is that CFS is the result of a malfunction of the nervous system in which the neurons are over-responsive to stimuli. Sounds, smells, bright lights, stress, etc. all over-stimulate the over-reactive nervous system, causing fatigue and adrenal exhaustion. This is certainly consistent with my own experience of the illness. The meds reduce synaptic transmission. Over time, they can restore the nervous system to normal functioning.
4 of 5 people found the following review helpful
Magnificent 8 July 2009
By Fred Thomas - Published on Amazon.com
Format:Paperback|Amazon Verified Purchase
My only complaint is that you have to read the whole thing cover to cover to make sure you don't miss anything. The book is less organized than its predecessor "Betrayal by the Brain" and the index, while at first glance appearing to be thorough, is quite incomplete.

I concur with another reviewer's statement about the information density. My notes on the book are book-length themselves. I especially love the 90 color figures that aid in understanding the anatomy and biochemistry involved.
4 of 5 people found the following review helpful
Two paragraphs contain more information than two pages of most books. 24 Jun 2009
By Steven Sponaugle - Published on Amazon.com
Format:Hardcover|Amazon Verified Purchase
Tuning the Brain

Two paragraphs of this book contain more neurochemical information than two pages of most books. Although I feel uncomfortable with the minimal attention Goldstein pays to detecting and treating the numerous viral, bacterial and fungal infections involved in Chronic Fatigue, Fibromyalgia, Irritable Bowel and Interstitial Cystitis, I feel his understanding of neurochemistry may be unparalleled. I would like to have read more about his experiences with intravenous Vitamin C treatment, which I believe may be the single most effective treatment for these disorders.

His diagnostic concept of quickly reaching the brain, by applying medications via ophthalmic, nasal and sublingual routes appears to have merit, since some of these sensory organs are only removed from the brain by two or three neurosynapses. The dramatically rapid improvements he describes using Naphazoline eyedrops, Nifedipine calcium channel blockers, sublingual Ketamine and other prescription medications are intrigueing.

Unfortunately Abecarnil and some of the other medications he discusses are not available in the United States, while others including Adenosine, with a ten second half life, would be of limited value, for chronic disease treatment.

Tragically, this brilliant, dedicated, devoted, unselfish physician reports he was unable to earn a living, testing and treating these very sick, labor intensive, exhausting patients, who have so many medical problems, requiring intervention after intervention. Health insurers and most patients do not want to pay for the level of care necessary to effectively treat these difficult patients for their numerous medical problems. Unfortunately, some of his patients were very selfish, demanding, manipulative and dishonest.

I recommend reading Betrayal by the Brain, before attempting to digest the incredible wealth of complex biochemical and neurochemical information in Tuning the Brain. I would not be surprised to learn that Dr. Jay Goldstein is awarded a Lasker or Nobel Prize when sufficient scientists succeed in comprehending the information he has written in this incredible book.

I was saddened to learn Dr. Jay Goldstein has retired, but am grateful for the outstanding contributions he has made to our understanding of neurochemistry, chronic pain, fibromyalgia, multiple chemical sensitivity, irritable bowel, interstitial cystitis, insomnia, anxiety, addiction and chronic fatigue treatment.

Steven Sponaugle

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