Three-dimensional Electron Microscopy of Macromolecular Assemblies [Hardcover]

Joachim Frank (Author)

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Product details

Hardcover: 330 pages
Publisher: Academic Press Inc (Jan 1996)
Language English
ISBN-10: 0122650409
ISBN-13: 978-0122650406
Product Dimensions: 24.1 x 16.5 x 1.9 cm
Amazon Bestsellers Rank: 4,506,231 in Books (See Top 100 in Books)

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Product Description

Three-Dimensional Electronic Microscopy of Macromolecular Assemblies is the first systematic introduction to single particle methods for reconstruction. It covers correlation alignment, classification, 3-D reconstruction, restoration, and interpretation of the resulting 3-D images oif macromolecular assemblies. It will be an indispensable resource for newcomers to the field and for all using or adopting these methods. Features: * Presents methods that offer an alternative to crystallographic techniques for molecules that cannot be crystallized * Describes methods that have been instrumental in exploring the three-dimensional structure of the nuclear pore complex, the calcium release channel,the ribosome, Chaperonins.

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Front Cover | Copyright | Table of Contents | Excerpt | Index

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3 of 3 people found the following review helpful

Crash Course in Single Particle Microscopy 20 Feb 2002

By Edmund Paley - Published on Amazon.com

Format:Hardcover

This concise and easy to read book is essentialy a crash course in single particle reconstruction by electron microscopy. It isn't exactly a how-to manual, more an overview of how the whole process works. Thus, it is useful not only to someone who wants to learn how to do this, but also to those who might be interested in deciding if this technique would be useful to them. And actually, the whole topic is sufficiently cool that I would recommend the book even to people who know they will never use this technique, just because its fun to read about it. The book is clearly written and doesn't assume alot of prior knowledge. A basic undergrad education in math would be enough to handle the equations.

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