Annual collections have evolved like dinosaurs from the slim volumes of the 60s and 70s into the paperback versions of Tyrannosaurs, vying for attention with their garish colour schemes (Sadly, the text for the cover of this issue completely obscures the artwork, looks like it's been thrown together hurriedly in a copy of Adobe Illustrator and doesn't do the volume itself any justice at all).
This series, ably edited by David G Hartwell, goes head to head with the Gardner Dozois series and a whole subspecies of other annual compilations which somehow survive to re-emerge next year, so good luck to them.
This volume purports to be the best SF of 2000. I say purports to be since the publishing history is a little strange, giving a first paperback publication date of June 2000, when some of the stories included were not published until July/August 2000. Looking at the publication dates of the stories included we notice that, yes, it seems that possibly all of the work included comes from a time before August 2000, which is unfortunate if your excellent SF story was published in, say, November 2000.
Odd.
This volume (no 6) comprises of:-
The Reef - Paul J McAuley (Skylife Ed Benford/Zebrowski 2000)
Reality Check - David Brin (Nature, Vol 404 2000)
The Millennium Express - Robert Silverberg (Playboy, Jan 2000)
Patient Zero - Tananarive Due (F & SF 2000)
The Oort Crowd - Ken MacLeod (Nature, Vol 406 2000)
The Thing About Benny - M Shayne Bell (Vanishing Acts, Tor 2000 Ed Ellen Datlow)
The Last Supper - Brian Stableford (Science Fiction Age, Mar 2000)
Tuberculosis Bacteria Join UN - Joan Slonczewski (Nature, Vol 405 2000)
Our Mortal Span - Howard Waldrop (Black Heart, Ivory Bones, Avon Books/Eos, Ed Ellen Datlow and Terri Wilding)
Different Kinds of Darkness - David Langford (F & SF, Jan 2000)
New Ice Age, or Just Cold Feet? - Norman Spinrad (Nature, Vol 405 2000)
The Devotee - Stephen Dedman (Eidolon #29/30 2000)
The Marriage of Sky & Sea - Chris Beckett (Interzone Mar 2000)
In The Days of the Comet - John M Ford (Nature, Vol 405 2000)
The Birthday of the World - Ursula K LeGuin (F& SF, Jun 2000)
Oracle - Greg Egan (F& SF, Jul 2000)
To Cuddle Amy - Nancy Kress (Asimov's, Aug 2000)
Steppenpferd - Brian W Aldiss (F&SF, Feb 2000)
Sheena 5 - Stephen Baxter (Analog, May 2000)
The Fire Eggs - Darrell Schweitzer (Interzone, Mar 2000)
The New Horla - Robert Sheckley (F&SF July 2000)
Madame Bovary, C'est Moi - Dan Simmons (Nature, Vol 407 2000)
Grandma's Jumpman - Robert Reed (Century, Spring 2000)
Bordeaux Mixture - Charles Dexter Ward (Nature, Vol 404 2000)
The Dryad's Wedding - Robert Charles Wilson (Star Colonies, 2000)
Built Upon The Sands of Time - Michael Flynn (Analog July/Aug 2000)
Seventy-Two Letters - Ted Chiang (Vanishing Acts, Tor 2000 Ed Ellen Datlow)