This is not a book to be undertaken lightly. Definetly not the sort of thing to read on your two weeks in the sun. Its 50+ chapters need to be read slowly, studied and digested. Hooper's thesis is that the AIDS virus is essentially a human invention. It mutated from the monkey version of HIV (SIV) when monkey kidney tissue was used to make Oral Polio Vaccines in the 50's. These vaccines were extensively tested in central and west Africa, the current epicenter of HIV and the disease spread from there. This is a brilliantly researched piece of work, describing both the history of HIV, AID and OPV research and the authors own journey to the source of the river of AIDS. I have only one grumble and that is the length. It is not an easy read. Hooper would undoubtedly find a much wider audience with a slightly less detailed work. The general reader does not need to know the detail of every OPV trial that took place in the 50s and the core of this work would not be lost for the lack of such detail. Nonetheless, a very important, beautifully written piece of work that will surely find its way to the bookshelf of anyone interested in science or the world around us and man's influence on that world.