The book explains in great detail the influence and the effect of mind over body from the perspective of neuro-biology. In simple terms, most healing performed with hypnosis are a result of mind influencing the blood-flow, which then creates corresponding changes in the body.
Rossi provides a some amazing case-histories where hypnosis has helped people deal with problems which were unresponsive to regular medical treatment.
Together with a number of healing techniques, the focus is on Ericksonian principle of utilization. In this respect he also points out the significance of "utradian rhythm" - the fact that throughout the day we all drift in and out of trance naturally, and that one could do hypnosis even more-effectively by doing it in accord with ultradian rhythm, at a time when the person feels naturally more relaxed and drifting into a trance state.