The book attracted me because of my layman's interest in neuroplacticity and because if its juxtaposition of cutting edge neuroscience with Buddhist thinking. Contrary to its title, however, the books is NOT a self-help book (which I did not think it was before I bought it); it is mis-titled, obviously for commercial reasons. One learns a lot about the the adaptability of the brain and its capacity to change or enlarge functions, e.g., to take over when a part of the brain is damaged or blocked. This is startling and as it is a developing science, it might be viwed as a well presented primer of neuroscience for an interested layperson. The first two-thirds of the book contain very little meaningful reference to Buddhism, but later on the comparative aspects of the scientific and Buddhistic view of the brain become more prominent, and, consequently, at least for me, more interesting. The author is a Newsweek journalist who seems at home with this complex scientific area, so presents it well. However, again I stress that both the title and the blurb may mislead a potential purchase into believing it is a blueprint for changing one's behavior. No, the book does not come with instructions for how to accomplish brain transformation.