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The Making Of Memory: From Molecules to Mind
 
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The Making Of Memory: From Molecules to Mind [Paperback]

Professor Steven Rose

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Steven Rose
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Book Description

Winner of the Rh-ne-Poulenc Science Prize

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Steven Rose's The Making of Memory is about just that, in both its senses:the biological processes by which we humans - and other animals, learn and remember - and how researchers can explore these mechanisms. But it is also about much more. When the first edition of this fascinating book won the Science book Prize in 1993, the judges described it as 'a riveting read...a first hand account by a practicing scientist working at the forefront of medical research and Rose does not duck the issues which that raises.' Now ten years on, research has itself moved forward, and Rose has taken the opportunity to fully revise the book. But this is more than mere revision. Where ten years ago he argued the case for research on memory because it is the most extraordinary of human attributes, Rose's own research has now opened the doors to a potential new treatment for Alzheimer's Disease undreamed of a decade ago, and in an entirely new chapter he describes how this potential breakthrough has occurred. (20030303)

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Amazon.com:  2 reviews
5 of 5 people found the following review helpful
Out of Date 14 May 2010
By Jiang Xueqin - Published on Amazon.com
Format:Paperback
This book was an award winner when it was first published in 1992 but since then neuroscience and psychology have advanced so far that this book is antiquated and irrelevant. It's annoying how the author keeps on talking about the biochemistry profession, and asks interesting questions but doesn't really answer them. For anyone interested in neuroscience check out "The Accidental Mind" or "The Female Brain" or "The Brain that Changes Itself".
15 of 22 people found the following review helpful
Are human memories stored in nucleic acids? 6 Oct 2000
By A Customer - Published on Amazon.com
Format:Paperback
We were taught in basic biochemistry that this question was answered in 1965 with a resounding, table pounding "No." Case closed. But on reflection, and at this remove in time, it is clear that the (rather appealing, really) possibility that nucleic acids constitute a long term memory storage medium was neither tested nor refuted 35 years ago. No one knew how. No one would know how today.

The author, who became deeply skeptical of the original 1960s research that launched the idea of nucleic acid memory -- tells the story of this forgotten controversy from a personal point of view, and this is the most interesting part of the book.

The fact is, biological information is very typically stored as sequences and shapes, and there is no reason to imagine the human memory is stored in some entirely different way. Probably the notion of nucleic acid memory will get a second hearing someday when we have the technology to actually test it, and some sort of a hunch or clue about how such a thing might work in the brain.

A fun book on the subject is the science fiction classic, "Hauser's Memory," and it is probably the only other book on nucleic acid memory that is still available.

For a quick, seamless review of the currently accepted view of human memory, which is grounded on the assumption that memory is stored as synaptic changes, see Kandel & Squire's book, "Memory. From Mind to Molecules."

For a sense of why the cherished assumption of synaptic memory will probably fail, and pretty soon, see the recent, mildly written but revolutionary book: "Spikes," by Rieke et al.


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