just did a quick read mar 99, and there is one very important nutrient that is not even mentioned that is more powerful than any of the b vitamins mentioned(folate, b12,b6) for lowering blood homocysteine levels. it is called TMG, or trimethylglycine, derived from sugar beets, which is CHEAP, and available at only a few health food stores. don't bother to ask your doctor about it; they are in the stone age WRT knowledge about nutrition, and they haven't even heard of homocysteine yet! there is a huge database of clinical support that shows just how powerful TMG is. TMG is a methyl-group donor, which degrades to DMG when it has donated one methyl group to homocysteine to render it harmless. it acts in DAYS to bring down the blood homocysteine level. dr. mccully deserves the nobel prize in medicine for his research and discovery, yet the establishment that ignored and ostracized him for so long will no doubt see to it that he either never receives it, or, like peyton rous, who received the nobel prize in 1966 for the cancer-causing virus he discovered in 1911(!),gets it very, very late. the homocysteine level test IS available, but must be specifically ordered by the physician. so you will have to find one who knows how important it is. rather strange, is it not, that a compound that the body(liver)makes for so many uses could possibly ever have been classified as a health hazard! i guess drug companies think that their totally non-natural drugs are better for you. the ridiculously simple experiment that was conducted years ago should have put to rest the cholesterol-as-villain myth--patients who had high cholesterol were given no diet or lifestyle changes, except that they were given vitamin c, at about 400-1000 mg/day, if i remember. guess what? their cholesterol plummetted.why? because in addition to all its other uses in the body, cholesterol is a first-line ANTI-OXIDANT, and so the body produces more of it when the diet is low in the main ones(a, beta-carotene, c,e, selenium). so within days of the body being helped out, the liver throttles back its cholesterol production! sea-changes in any discipline take decades, if not centuries, to come around. hopefully, within a few years, blood tests for homocysteine will be as routine as the WBC or RBC tests are now.