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Review
This is an impressively thoughtful, beautifully balanced analysis of where we stand today in the critical attempt to understand, and thereby defeat cancer as a scourge on humanity. Not only is it the perfect text for a serious course on cancer biology, it should be read by every cancer researcher - Bruce Alberts, University of California, San Francisco, USA
The Biology of Cancer is no doubt the definitive statement on its topic today. -Science, 11 August 2006: Vol. 313. no. 5788
There is no comparable text in cancer biology and no single book that is so current and informative. -Nature, November 30, 2006, Vol 444
'The Biology of Cancer, written by the distinguished American cancer biologist Robert Weinberg, is by far the most extensive of these new works and, as the product of a single author, is a remarkable achievement. The book is beautifully illustrated in full colour and well supplied with key review articles. It is extremely well written in language that should be accessible to the non-expert. Overall, this is a remarkable achievement that is by far the most comprehensive coverage of this field available.' - The Times Higher Education Supplement, February 23rd 2007
"The breadth of the topics covered, the clear writing style, the logical organization and the beautiful figures make The Biology of Cancer a classic text for any biologist interested in cancer...An additional strength of the book is the multimedia CD...¦Thus, The Biology of Cancer is not only a great read but also an outstanding learning tool."-Nature Cell Biology (November 2007) vol. 9, no. 11
Product Description
The Biology of Cancer is a textbook for undergraduate and graduate biology students as well as medical students studying the molecular and cellular bases of cancer. The book presents the principles of cancer biology in an organized, cogent, and in-depth manner. The clarity of writing and the lucid full-color art program make the book accessible and engaging. The information unfolds through the presentation of key experiments which give readers a sense of discovery and provides insights into the conceptual foundation underlying modern cancer biology.
The Biology of Cancer synthesizes the findings of three decades of recent cancer research and proposes a conceptual framework from which to teach about these discoveries. It provides the necessary structure, organization, and content for a course on cancer biology for advanced undergraduates and beginning doctoral students. The book is comprehensive and offers many pedagogical features to assist teaching and learning. The book includes many recent and topical references, and is intended to empower the student to move directly into the primary research literature.
The text is up-to-date and provides current information on topics such as tumor stem cells and recently introduced chemotherapeutics. State-of-the-art techniques are discussed throughout. Modern biomedical research is explored, helping readers to hone their analytical abilities and to assimilate and think clearly about complex biological processes. The Biology of Cancer provides insights into many aspects of immunology, developmental biology, and neurobiology.
The exceptional full-color art program contains many images published for the first time. The book is extensively illustrated with schematic drawings, micrographs, computer-generated models and graphs. The pieces were chosen to support and clarify the concepts, as well as to supply additional interest.
Besides its value as a textbook, The Biology of Cancer will be a useful reference for individuals working in biomedical laboratories, and for clinical professionals.
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Customer Reviews
The chapters follow a natural order, but the book certainly doesn't need to be read linearly - one can dip in and out of chapters with ease, since each is 'relatively' self-contained. I would say though, if you are a beginner, it would be best to at least read the first few chapters for a solid grounding in the basics (i.e. fundamental genetics, the idea of mutations, and the multistep and clonal origin of cancer).
The author not only gives an account of the diseased state but also of the biological processes which are disregulated in cancer. These include apoptosis, cell signalling and cell cycle control. The book covers many different sciences from structural biology to histological analysis of tissue, but all are relevant to the underlying discussion of cancer.
The style of writing is easy to read, and it often feels more like a story than a factual assault. However, this style does mean you may have to read multiple paragraphs to get a point which could have been described in a few sentences. Nevertheless, i would not consider this a failing - it makes the read more enjoyable and therefore more informative.
The diagrams are excellent, especially the summary diagrams of signalling networks. Weinberg also includes many tissue sections and pictures from primary literature and well as protein structures. This broadens our horizons - the biochemist will get an insight into medical oncology while the medic will be informed about signalling and cancer at the level of protein interactions. This book really does have it all.
The 'Synopsis and Prospects' sections at the end of each chapter are always interesting to read. They give an overview of the chapter and provide more insight and future directions. A list of bullet points summarising the key concepts and the thought questions are also useful for revision. References are provided but these are very limited, perhaps due to the vast body of literature that is out there. The glossary and list of abbreviations are useful and this book is not without its own self-indulgent quotations at the start of each chapter.
Who is this book for? I am a final year undergraduate in biochemistry and molecular biology and this book was perfect as an introduction to cancer. After reading this (or parts of this) i felt confident about tackling the primary literature - an otherwise daunting task, given its size. I'm sure it would also be useful to medical and biology students, both undergrads and others moving into the field. In fact, anyone with a general interest in cancer (as long as they have a reasonable scientific background) would greatly benefit from reading this marvelous book.
As a medical student doing research .... this book was a great help in understanding many principles about Molecular basis of... Read more
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