Please take into account that everyone has their own taste and perceptions about literature, so take what I say, with a grain of reduced sodium. First, I would give 5 stars to Rucker's Books such as Saucer Wisdom, and Hylozoic, and 4 stars to Jim and the Flims. 4 for Jack and the Aktuals (sp?) 5 for Mathematicians In Love. If somebody here, has even a speck of feelings for the old timey religions (and I am not saying you should!) then the cosmology-theology-biology of AHA is a bit disappointing. But it did not ruin the novel, by any means. For any hints of this, as not to ruin the plot for anyone, all I need say is "All Hail The Magic Pig!"
The story line, to be concise, is a hybrid between a technology of gene modification, synthetic biology, in the decades ahead, ehich eventually, gets plugged into telepathy, and other worlds/dimensions. Nicely, bundled together, with the culture of the 1960's (man!). Do I recommend a buy for the novel? Hell, yes! Turn on, tune in, and download (man!).