I found this book enlightening. True, as another reviewer said, it's not all that *original*, nor is it written absolutely well. However, I think it's wrong to think that most people are familiar with this concept. Well, lots of people may be, but so many people I know who are familiar with reductionism reject it for no more reason than a general feeling of "dislike". When I read it a few years ago, I found it enlightening to find someone so excited and astonished by something that most people find frightening. I loved his scientific view of the natural beauty the hypothesis suggests.
I'd also like to point out that, while reductionism itself may be "centuries old", Crick's deep examination and presentation of evidence in favor of an actual neurological basis for what we think of as the "soul" is only as old as neurology.
I wouldn't recommend this book to just anyone. But I would recommend it as a starting point -- just borrow it ! from your library, read the introduction, the conclusion, the bibliography, and go from there!