I've been studying Czech out of this book since July 2006. It's the only comprehensive overview of the Czech language out there, and it's great. The book is very well written and edited. It's very concise and explains everything you need to know about the language in a logical and sequential way. If you are truly devoted to learning the language in depth, this is the book for you. Be aware however, you will need to make flashcards, listen to Czech internet radio and rent Czech movies, take notes from the book, and perhaps purchase Josef Fronek's Czech-English dictionary. If you really want to put the time in - this is the book for you. But it's VERY difficult, and is like doing a Sudoku puzzle every time you sit down to read it.
If you just want to learn a couple of useful phrases, check out the in-flight Czech CD or Berlitz's tape on Czech expressions. Stay away from the Pimsleur 5CD set, because it's extremely boring.