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Synthetic Biology - A Primer [Paperback]

Paul S. Freemont , Richard I Kitney , Geoff Baldwin , Travis Bayer , Robert Dickinson , Tom Ellis , Karen Polizzi , Guy-Bart Stan , Richard I. Kitney
4.2 out of 5 stars  See all reviews (4 customer reviews)
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Book Description

4 Aug 2012 1848168632 978-1848168633 1
"Synthetic Biology - A Primer" gives a broad overview of the emerging field of synthetic biology and the foundational concepts on which it is built. It will be of interest to final year undergraduates, postgraduates and established researchers who are interested in learning about this exciting new field. The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely 'bottom-up' and 'top-down' engineering approaches. 'Top-down' engineering utilises a conceptual framework of engineering and systematic design to build new biological systems by integrating robustly characterised biological parts into an existing system through the use of extensive mathematical modelling. The 'bottom-up' approach involves the design and building of synthetic protocells using basic chemical and biochemical building blocks from scratch. Exemplars of cutting-edge applications designed using synthetic biology principles are presented, including the production of novel biofuels from renewable feedstocks, microbial synthesis of pharmaceuticals and fine chemicals, and the design and implementation of biosensors to detect infections and environmental waste. The book also uses the Internationally Genetically Engineered Machine (iGEM) competition to illustrate the power of synthetic biology as an innovative research and training science. Finally, the primer includes a chapter on the ethical, legal and societal issues surrounding synthetic biology, illustrating the integration of social sciences in synthetic biology research.

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Synthetic Biology - A Primer + Regenesis + Creation: The Origin of Life / The Future of Life
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Product details

  • Paperback: 250 pages
  • Publisher: Imperial College Press; 1 edition (4 Aug 2012)
  • Language: English
  • ISBN-10: 1848168632
  • ISBN-13: 978-1848168633
  • Product Dimensions: 24.4 x 16.5 x 1.3 cm
  • Average Customer Review: 4.2 out of 5 stars  See all reviews (4 customer reviews)
  • Amazon Bestsellers Rank: 479,518 in Books (See Top 100 in Books)
  • See Complete Table of Contents

Product Description

From the Back Cover

 In Synthetic Biology, expert researchers in the field provide the latest developments in molecular biology techniques used in Synthetic Biology.  Focusing on computational tools that will aid in systematising the design and construction of parts and systems. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.


Authoritative and practical, Synthetic Biology seeks to aid scientists in the further study of developing new biological components and systems.

--This text refers to the Hardcover edition.

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Customer Reviews

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Most Helpful Customer Reviews
1 of 1 people found the following review helpful
5.0 out of 5 stars Good overview! 8 Jan 2014
Format:Paperback|Verified Purchase
Good starting point if you're new to the field since it is interdisciplinary, this book offers basics on the various topics and application opportunities of SynBio!
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4.0 out of 5 stars Four Stars 15 Aug 2014
By JohnnyK
Great introduction to synthetic biology, combining the biology and engineering aspects into one coherent whole.
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1 of 2 people found the following review helpful
4.0 out of 5 stars A first impression 4 Oct 2012
Format:Paperback|Verified Purchase
I find this book quite well structured. The first impression is very favourable. It introduces the subject in ways that make it accessible to newcomers to the area. The text is carefully written an pleasant to read.Good illustrations. The subject is seen from various perspective which is also very helpful.
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0 of 7 people found the following review helpful
4.0 out of 5 stars good introduction 28 Aug 2013
By 567a
Format:Kindle Edition|Verified Purchase
Since I am required to submit a review before finishing the book, I can't say too much right now really.
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Most Helpful Customer Reviews on (beta) 3.7 out of 5 stars  3 reviews
15 of 15 people found the following review helpful
4.0 out of 5 stars Good overview of and introduction to synthetic biology 13 Sep 2012
By catfish - Published on
Format:Kindle Edition|Verified Purchase
I am currently working my way through the kindle version of this book, and am approx. 40% of the way through. It is a good introduction and I'm learning a lot from it. One thing to be aware of; it is quite technical and launches rapidly into both molecular biology and engineering. Be prepared to work at understanding and look things up online if you aren't already familiar with both areas. There's some advanced math - Fourier transforms, for example, though they aren't essential to understand most of what is in the book. If you aren't familiar with biology I recommend reading a text on cellular or smaller-scale biology first.
3.0 out of 5 stars Not for the Layman 3 Jun 2014
By Leo Roos - Published on
Format:Kindle Edition|Verified Purchase
This book cannot be considered a primer. It reads well, but unless you are an expert in the field you are at a loss of what is a futuristic discussion and what is possible today.

Unless you have a decent background in statistics, computer analysis and chemistry, the discussions will befuddle many of you.

Cannot fault the layout or the topics or the writing style. However, as stated earlier it is aimed at those that have more than just a basic understanding of the aforementioned subjects to really understand the intent and discussions in the book.

Leo Roos, Ph.D.
4.0 out of 5 stars Textbook 10 Feb 2014
By Ashley - Published on
Format:Kindle Edition|Verified Purchase
Covers many relevant aspects of biology, clear descriptions. Worked well as a teaching tool for both undergraduate and graduate students.
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