"Synthetic Biology - A Primer" gives a broad overview of the emerging field of synthetic biology and the foundational concepts on which it is built. It will be of interest to final year undergraduates, postgraduates and established researchers who are interested in learning about this exciting new field. The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely 'bottom-up' and 'top-down' engineering approaches. 'Top-down' engineering utilises a conceptual framework of engineering and systematic design to build new biological systems by integrating robustly characterised biological parts into an existing system through the use of extensive mathematical modelling. The 'bottom-up' approach involves the design and building of synthetic protocells using basic chemical and biochemical building blocks from scratch. Exemplars of cutting-edge applications designed using synthetic biology principles are presented, including the production of novel biofuels from renewable feedstocks, microbial synthesis of pharmaceuticals and fine chemicals, and the design and implementation of biosensors to detect infections and environmental waste. The book also uses the Internationally Genetically Engineered Machine (iGEM) competition to illustrate the power of synthetic biology as an innovative research and training science. Finally, the primer includes a chapter on the ethical, legal and societal issues surrounding synthetic biology, illustrating the integration of social sciences in synthetic biology research.
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Format:Paperback|Amazon Verified Purchase
I find this book quite well structured. The first impression is very favourable. It introduces the subject in ways that make it accessible to newcomers to the area. The text is carefully written an pleasant to read.Good illustrations. The subject is seen from various perspective which is also very helpful.
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7 of 7 people found the following review helpful
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Good overview of and introduction to synthetic biology
13 Sep 2012
By catfish
- Published on Amazon.com
Format:Kindle Edition|Amazon Verified Purchase
I am currently working my way through the kindle version of this book, and am approx. 40% of the way through. It is a good introduction and I'm learning a lot from it. One thing to be aware of; it is quite technical and launches rapidly into both molecular biology and engineering. Be prepared to work at understanding and look things up online if you aren't already familiar with both areas. There's some advanced math - Fourier transforms, for example, though they aren't essential to understand most of what is in the book. If you aren't familiar with biology I recommend reading a text on cellular or smaller-scale biology first.
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