This is the continuing love story between a cocky travelling merchant named Lawrence and his travelling companion, Holo the wise wolf, a pagan goddess he met in season 1. It's a story told across an unusual backdrop of markets economics, intrigue and a little touch of mystery. The characters are strong willed and sympathetic, and you will soon find yourself drawn into their story.
An excellent anime, with interesting plots and character arcs, it's attractively drawn and has decent dubbing too. This season I felt was paced much more solidly than the first (which makes it all the more disappointing that there is no anime season 3! I believe that season 2 of the anime ends at around the 6th Spice and Wolf book if you want to carry on the story but I'd suggest you check that for yourself.)