I would like to begin by saying that I am not sure if joysticks in general are recommended for use in patients with RSI or carpal tunnel syndrome. I am sure however that they are designed for use in space flight and air flight simulator games, and in this respect this joystick excels.
Briefly, this Saitek Cyborg V1 has 7 buttons, an 8-way point of view hat, a throttle lever and a 'twist' rudder (twist the stick to turn the rudder) in addition to the usual x- and y-axes. On paper therefore this is an excellent joystick, incorporating every feature I could think of.
How is the performance in games? I have tested this in Wing Commander Prophecy, Wing Commander Secret Ops and Freespace 2. In all three games I have experienced no problems. (Only one minor complaint in WC Secret Ops: for some reason, if I invert the rudder in the game to change the behaviour to what I expect, it does not remember the setting.) I especially appreciated the twist rudder, which allows me to roll while banking/pitching -- useful for 'evasive' manoeuvres.
The feel of the joystick is good; it is easy to move, and auto-centres.
In the past I have used very cheap joysticks: e.g. 2-axis 2-button joysticks. These suffered from some major problems: even at rest, the joystick signal 'trembles', so it was difficult to fly in straight lines when using them. They would have good gradation of movement in one direction (e.g. left) but if moved in the opposite direction (e.g. right) the movement would be maximum, so making them difficult to aim with. Finally, the auto-centre mechanism would break. These problems would manifest themselves after 6-months to a year's worth of (admittedly heavy) playing.
So far I have encountered none of the above problems. I have been using the joystick moderately for about 3 months, so I cannot give information about long-term durability.
The joystick has excellent compatibility. It connects via a USB port. I have tested in in Windows XP SP3, Windows Vista SP1 and Kubuntu Linux 10.04. They all immediately recognise the joystick.
The only minor quibbles I have with this joystick are: there is a blue LED light where the trigger button is; this might annoy you in a dark room as it illuminates what's behind your monitor. Also, it has a wide base which requires (very simple) assembly, but cannot be easily disassembled. Therefore, it takes a moderately large amount of area on your desk (about a square of side-length 24cm) and is not easy to transport long distances (e.g. by car).
In summary, this is a very capable joystick, and I would wholeheartedly recommend it to any occasional or moderate gamer -- especially given the phenomenal value for money (at time of writing this cost just £20)!