Together with junky, Queer is the most accessible book Burroughs has written. They are his two first works, although Queer was not published until 1985, due to its dealings with homosexuality.
These two books are probably those texts where Burroughs is most connected with the Bet Generation, even if he is said to have been one o the Founding Fathers for the movement, together with Kerouac and Ginsberg. They were written before his cut-up method was created and are quite traditional in their narrative structure.
Queer is the sequel to Junky, where we hear what happens to William Lee in Mexico. The story deals with Lee trying to get off drugs and on to boys, but things do not always turn out that way. However, in comparison with Junky we hear very little about drugs and a lot about homosexual acts.
All in all, a good book, with Burroughs telling his stories as only he can do it. If you enjoy his later works, this book is an interesting iew of how he wrote before and how many of the same themes are still explicit already here.