Mix together a bit of Alice in Wonderland, the Shakers, jazz improvisation, nanotechnology, plus traditional post-apocalypse sci-fi and you get Queen City Jazz.
It sounds like a mess and it almost is. However, scientifically implausible ideas are kept together by a keen sense of the surreal and the absurd. While the book is too long, there are passages full of evocative beauty.
All in all, a very ambitious first novel, whose ambitions are so high that it is bound not to reach them. It isn't as good as the best bio- / nanotech sci-fi, in particular Paul J McAuley's 'Fairyland', but remarkable enough to merit 4 stars.
(On a final note, I wonder whether Jeff Noon read this before writing 'Pollen'. Although unavailable in the UK at the time, it had already been published in the USA, and there are enough similarities to make me suspicious... perhaps it is just coincidence?)