This is a great idea. The box design and promise of the gameplay is enough to satisfy a die-hard poke-fan. In practice the flaws show up, especially compared to the MB Games original with invented people characters.
The plastic is quite flimsy, and it's tricky to flip up the panels without knocking others over. There are 2 sets of cards, with different Pokemon in each - so in reality half the Pokemon aren't in the game. You could play with 2 sets mixed, as long as you made sure you were guessing from the right set. For the most part, you'll keep one set in... as unlike the MB verison where the cards are clipped permanently in place, these are just slid in and keep dislodging themsleves (they are designed to be switched with the other set of Pokemon).
If you can get over this - as we did, the real flaw of the game is in the difficulty of getting a reliable YES/NO answer from a given question, as there aren't enough firm differences between the pokemon apart from number of legs and type of Pokemon (fire water etc) - they don't have carefully worked out discrete traits that can be easily verified like in the MB version. Also the evolutions of some pokemon, eg Pichu and Pikachu are so similar it is really hard to find anything to clearly separate them. The problem lies in the nature of pokemon themselves. Recommended for real hardcore fans of the pokemon who will obviously overlook these shortcomings without question.