Neal Barrett, Jr. is well known to me as a SF/Fantasy writer, but until just recently I was unaware of his mystery novels. _Pink Vodka Blues_ is the first I have read. It would seem from internal evidence that it is not part of an ongoing series.
The lead character is Russell Murray, a seriously alcoholic writer for a literary magazine in Chicago. He returns from a trip to Dallas for his editor with absolute no memory of where he's been or what he's done. Worse, he wakes up in a hotel room with a woman he doesn't recognize -- and minutes later a couple of hitmen smash there way into the room and kill the woman -- Russell escapes in terror by sheer luck. Naturally enough, he is soon the prime suspect in the murder of the woman, and he is quickly on the run. He still has no idea what happened in Dallas -- he was supposedly delivering a manuscript to a reclusive author while his editor, who was supposed to do the job, spent the weekend with his girlfriend. Soon Russell learns that his editor is the nephew of a local mob boss, and that two factions in the mob want whatever Russell was supposed to deliver, which delivery apparently never happened. Russell can't help, because his memory is shot. He ends up in a rehab facility after passing out in his car -- and there he meets a beautiful and rich alcoholic woman. When the mob track him down, he and the woman escape, and rather clumsily and drunkenly wend their way across the US, to Dallas, Florida, and back to Chicago, chased by two strange sets of hit people, trying to figure out what Russell has forgotten.
The book is quite funny at times, though it's also a scary (and accurate seeming) portrayal of alcholism. The main characters are nice enough that we root for them, but they are by no means hero and heroine -- they are losers, and if they end up halfway solving their problem, only some of the bad guys get their due, and the good guys only partly get a happy ending also. Which qualifies as fairly realistic, I guess. This fits more or less into the Elmore Leonard end of the crime fiction genre, though I'd call it not as good as Leonard, but worth reading.