As a complete novice to both PHP and MySQL, I found this book totally accessible. [The last language I learned was - wait for it- FORTRAN! - things have moved on a bit...] The progressive tutorial was paced at a perfect rate, introducing just enough new material each time to keep the interest level high and not too much to be overwhelming (unlike a lot of other computer books). The database section of the book explained relational databases in understandable and practical terms too. Another good feature is the wealth of good quality reference material, encouraging the reader to supplement knowledge in specific areas if desired. The overall thrust of the book is towards what I, and I imagine a lot of others, want to do - make a database driven website. The book succeeds in this objective very well indeed.
It's also a very handy reference to Open Source PHP, which helped me to understand how to configure and use several packages.
My only slight criticism is the lack of detail when discussing security - something which is surely a top concern of any operational website. Apart from that, I can't praise it highly enough. If only all computer books were written like this.....