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Product Description
The ability to design effective syntheses is an essential skill for organic chemists. This valuable text uses a wide range of examples to teach students of chemistry how to adopt a logical and versatile approach to the design of synthetic routes. The concept of retrosynthetic analysis - a means for identifying simple starting materials for a synthesis - is first introduced with emphasis on the importance of bond polarity and functional group interconversions. The next section describes how an effective route to a target molecule containing more than one functional group can be elucidated, and gives useful strategies to adopt when designing syntheses. Later chapters review methods for the control of chemo-, regio-, and stereoselectivity, and include a discussion of protecting groups. Finally, four syntheses of the pyrrolidine alkaloids are compared and contrasted using the principles described in the book. Practice examples are provided throughout, making this concise text an invaluable study aid for all undergraduate chemists.
About the Author
Chris Willis and Martin Wills are both at the University of Bath.
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First Sentence
In 1965 Professor R.B. Woodward was awarded the Nobel Prize for his contributions over many years to 'The Art of Organic Synthesis', an apt description of a science which requires creativity and ingenuity as much as logical analysis. Read the first page
Front Cover | Copyright | Table of Contents | Excerpt | Index | Back Cover
In 1965 Professor R.B. Woodward was awarded the Nobel Prize for his contributions over many years to 'The Art of Organic Synthesis', an apt description of a science which requires creativity and ingenuity as much as logical analysis. Read the first page
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Front Cover | Copyright | Table of Contents | Excerpt | Index | Back Cover
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Customer Reviews
Most Helpful Customer Reviews
3 of 7 people found the following review helpful
Format:Paperback
I enjoyed the style of the book, and it corresponded well to my course at university.
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1 review
3 of 3 people found the following review helpful
91-Page small masterpiece on a large topic
15 Mar 2008
Format:Paperback
Like many other items in this Oxford chemistry primers, this one is of particlar value among those heavy big volumes on this topic. As precise as it could be - 91 pages, it has covered all the major points of organic synthesis in terms of retrosynthesis analysis and selectivity, as well as representative published works. The authors also pay attention to touch on different reactions as many as possible - after all mastering reactions is a must for successful synthesis. The best feature is the logical presentation of the topic which allows the readers to actually enjoy reading without much difficulty - with gradual increase of depth to the final original publications. Of course such a volume is not intended for those who are very experienced in the art of organic synthesis. Rather, it could be very refreshing and helpful for the experienced ones to pick up this topic again after a while away from this field. Or it could serve as a valuable piece for an organic chemistry student prior to formal graduate level organic synthesis. Or test yourself if you understand all the material in this book - if the answer is yes, you should be a proud synthetic organic chemist already!
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