I came to Christopher Brookmyre rather late in life (nine of his books already in paperback, and the tenth about to be published), but I have read all eleven in the past twelve months or so, and have found this to be one of his best. I have read his books in chronological order, so this was one of the first, and the first that wasn't about Jack Parlabane. Having recently finished his first two books, I started this with a little trepidation - it seemed odd to start off with that there was no sign of Parlabane (though he does get the briefest of mentions as being a good friend of lead character Steff Kennedy) - but I soon settled into things, and discovered that, actually, things were better without him.
There are times when the plot gets slightly TOO far-fetched (hey, it's a Brookmyre), but it still manages to stay just about this side of plausible, which certainly can not be said of one or two of his later offerings (I'm thinking All Fun & Games as a for instance). I have read comments about "Americans with a British accent" being a problem, but it certainly wasn't for me. Far harder, I think, for American authors to pen British characters.
As time has gone on, presumably Mr Brookmyre has found it harder and harder to come up with plausible plots (the latest Rubber Ducks episode being the lowest point yet), but then, we are talking fiction here, so does it really matter how implausible the plot is?