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Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics [Paperback]

Lauren Pecorino
4.4 out of 5 stars  See all reviews (10 customer reviews)
RRP: 34.99
Price: 28.89 & FREE Delivery in the UK. Details
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Book Description

26 April 2012 019957717X 978-0199577170 3
Cells in our body undergo tightly regulated replication to enable growth to occur in a precise, and to ensure that damaged or worn out tissues are replaced. Regulation is mediated via many different mechanisms; it is when these mechanisms fail, and regulation is lost, that cancer can result. Recent advances in molecular cell biology have greatly expanded our understanding of the processes and mechanisms which underpin the regulation of cell replication, and what is happening at the molecular level when these fail. The third edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents. Opening with an overview of the key hallmarks of cancer as a disease state, the book then leads us through the principal processes that become altered in cancer cells, and explains how the failure of these processes can lead to the onset of cancer. Uniquely, within each chapter, students are shown how this molecular knowledge is being applied to develop new targeted therapeutic strategies. Written with the student learner in mind, the book features a variety of learning features to help students engage with, and master, the concepts presented. The emphasis is not on exhaustive coverage of the field, but on acquiring a solid understanding of the essentials of the subject - and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit. The Molecular Biology of Cancer is an invaluable resource for any student wishing to gain an insight into the molecular basis of the disease, and possible solutions for its effective control. Online Resource Centre The Online Resource Centre to accompany The Molecular Biology of Cancer features: For students: * Hyperlinks to primary literature articles featured in the text * News feeds relevant to cancer biology, drawn from a variety of publications For registered adopters of the book: * Figures from the book, available to download * A test bank of questions, with feedback linked to the book, for use in formative or summative assessment

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Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics + Clinical Biochemistry (Fundamentals of Biomedical Science)
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More About the Author

Lauren Pecorino was born in New York City and grew up on Long Island, NY. She received her PhD from the State University of New York at Stony Brook in Cell and Developmental Biology. She crossed the Atlantic to carry out a postdoctoral tenure at the Ludwig Institute for Cancer Research, London. She is a Principal Lecturer at the University of Greenwich where she greatly enjoys teaching a course called: Cancer Biology and Therapeutics. The teaching of this course motivated her to write a university textbook called "The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics, published by Oxford University Press. The text has been translated into several languages and is now in its second edition. Feedback on the textbook posted on Amazon from a cancer patient drove her to write a book on cancer for a wider audience. Her latest book, Why Millions Survive Cancer: the successes of science, is for those who are interested in science and well being. She hopes it will make a difference to your life.

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Review

Dr. Pecorino has done a fantastic job... The book's engaging writing-style and well thought out structure welcomes anyone with an interest in studying cancer in thorough, interesting detail. Reading this text was a pleasure, benefited me greatly educationally and made me feel like being a real part of the teaching - as though things were being explained to me in a one-on-one tutorial, an experience that most other medical textbooks don't provide! Amazon.co.uk reviewer Reviews of previous edition: Pecorino gets the balance right between cell and molecular biology, focusing on mechanism rather than disease. Importantly the students like the text and can afford to buy the book. Therefore it is a real support to our learning program and actually used by the students. Dr Bernard Mahon, Biology Department/Institute of Immunology, National University of Ireland Review from first edition The author's infectious enthusiasm as a teacher comes across on every page of this beautifully illustrated book. To guide her readers through this increasingly complex field, she introduces some novel features, including "Special interest" boxes, sections labelled, "Pause to think," well-designed chapter highlights and aids to "Memory refreshment." Given the speed of development of this field, the book is remarkably up to date. Sir David Weatherall, Emeritus Regius Professor of Medicine, Oxford University in THES Textbook Guide - February 2006

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Customer Reviews

Most Helpful Customer Reviews
2 of 2 people found the following review helpful
Format:Kindle Edition|Verified Purchase
This book is very concise, and extremely relevant to the Masters programme I have just commenced in Clinical Oncology. Having come from a nursing background, this book provides the appropriate level of learning for my needs, but for those in more advanced positions also. The author is obviously very passionate about both teaching and Oncology, and this enthusiasm helps in the reading and learning process. The book is full of fantastic reference sources, which will come in very useful for my assignments I am sure. The book's size means that I can take it with me to read on the train without causing a shoulder injury, which is a bonus.
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1 of 1 people found the following review helpful
5.0 out of 5 stars for all specialty 1 Feb 2014
Format:Paperback|Verified Purchase
very good book really, love it.
interesting for all specialties , i bought it for my wife, now i am reading it.
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1 of 1 people found the following review helpful
5.0 out of 5 stars facilitate systematic understanding of cancer 2 Jan 2014
By Olivia
Format:Paperback
I found that your book `molecular biology of cancer' is really helpful for understanding cancer biology systematically.
There are tight connections between different conceptions in this book and I can see a clear story line which really do benefit to my learning. And there are latest progress to support the principle which means that the author can connect the research news to previous knowledge and have the ability to evaluate them.
This evaluation benefits me as well since it hints the logic and method of learning.
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1 of 1 people found the following review helpful
5.0 out of 5 stars This is a fantastic Book 19 Nov 2013
Format:Paperback|Verified Purchase
I ordered this book from "the Full Monty" but never received it. I did however borrow it from the university library whilst waiting for the ordered one to arrive. A really good book about the subject. very clear explanations.
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1 of 1 people found the following review helpful
5.0 out of 5 stars a readible book 22 May 2013
Format:Paperback|Verified Purchase
i recommend this book to most of the students who needs to learn the cancer subject. it has a very clear way of teaching in simple but in scientific ways with the illisturations well drawn.
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