A gray and dystopic future, evil megacorp taking over the world and the people in it - OK, that part's been done. 'Metropia' stands out for doing it brilliantly. It's a lot more than that, though.
Animation has explored the super-realistic, with just enough success that the discrepancies become especially jarring. This goes farther, well into the surreal. That allows for exaggerations of faces and figures, wide-eyed blankness and evil scowls that wouldn't be phyiscally possible for human actors. And, despite great advances in computer-aided post-production, animators can build their worlds from the ground up in the image they want, with no need to retrofit them into scraps of reality. This movie really does use animation in a novel and very distinctive way.
Very enjoyable in many ways. Certainly not one for the kiddies, it scarcely qualifies as as "adult" movie - but body-shy viewers might have trouble with brief- and semi-nudity.