This is an interesting work that to an extent builds on Austin's three previous works
Zen and the Brain,
Zen-Brain Reflections and
Selfless Insight: Zen and the Meditative Transformations of Consciousness. It is a much smaller volume and has a far more practical orientation, being aimed at the practitioner with an interest in the underlying neural aspects of practice. The work provides useful advice based on the latest neurological understanding of how various systems in the brain work and how meditation effects this functioning.
It is perhaps useful to have read and own the previous works, as they are cross-referenced in this volume, however I don't believe it is strictly necessary and I am sure any interested meditator will find a lot of useful information in this work.
"This extraordinary book on meditation is a perfect jewel, shedding light for the reader on the intricate and profound craft of the practice of meditation and the neuroscience of meditation. It is a book like no other in the field and is due to become a classic. It is exceptionally useful, beautifully written, rich with anecdotes, and full of surprises."
-Roshi Joan Halifax, Founding Abbot, Upaya Zen Centre
"Here James Austin brings the fruit of his many decades engaging Buddhist meditation as a living practice, while at the same time examining what happens in the brain during meditation. This book is inviting and challenging at the same time and will prove valuable for both the novice and the long time meditator. I highly recommend it."
-James Ishmael Ford, author of Zen Master Who: A Guide to the People and Stories of Zen