- Hardcover: 264 pages
- Publisher: Harvard University Press; 1 edition (13 Jan 2012)
- Language English
- ISBN-10: 0674061586
- ISBN-13: 978-0674061583
- Product Dimensions: 24.8 x 16.6 x 2.8 cm
- Amazon Bestsellers Rank: 1,929,518 in Books (See Top 100 in Books)
Long Shot: Vaccines for National Defense
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Innovations in research and development and the importance of vaccines to public health--second only to clean water--are vital issues...All citizens need to know more about these subjects. -- Mary Chitty Library Journal 20120215
Product Description
At the turn of the twenty-first century, the United States contended with a state-run biological warfare program, bioterrorism, and a pandemic. Together, these threats spurred large-scale government demand for new vaccines, but few new have materialized. A new anthrax vaccine has been a priority since the first Gulf War, but twenty years and a billion dollars later, the United States still does not have one. This outcome is as puzzling as it is troubling. Historically, the United States has excelled at responding to national health emergencies. World War II era programs developed ten new or improved vaccines, often in time to meet the objectives of particular military missions. Probing the history of vaccine development for factors that foster timely innovation, Kendall Hoyt discovered that vaccine innovation has been falling, not rising, since World War II. This finding is at odds with prevailing theories of market-based innovation and suggests that a collection of nonmarket factors drove mid-century innovation. Ironically, many late-twentieth-century developments that have been celebrated as a boon for innovation--the birth of a biotechnology industry and the rise of specialization and outsourcing--undercut the collaborative networks and research practices that drove successful vaccine projects in the past. Hoyt's timely investigation teaches important lessons for our efforts to rebuild twenty-first-century biodefense capabilities, especially when the financial payback for a particular vaccine is low, but the social returns are high.
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1 of 1 people found the following review helpful
An incredibly well-researched account of the search for vaccines for national defense.
2 Feb 2012
Format:Hardcover|Amazon Verified Purchase
Hoyt meticulously and eloquently recounts the evolution of vaccines for national defense in a way that is both informative and interesting to read. I learned so much from this book trust it will become a standard text in the discussion of national defense.
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