It's only my first day using the mouse, but I know it'll do the job. For people that have owned an Evoluent mouse in the past, you hold it almost exactly the same way (almost as if you're shaking someone's hand).
As I have owned 2 Evoluent mice in the past, I know that this works for me, eliminating arm/shoulder pain (and it's a quarter of the price of the Evoluent!)
It doesn't receive 5 stars because it only has 2 buttons... a programmable thumb button would've been nice, given that there's so much space.
Something to look forward to for the Accuratus V2 then :)