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Introduction to Genetic Analysis Hardcover – 24 Dec 2010

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Hardcover, 24 Dec 2010
£105.27 £93.66
--This text refers to an alternate Hardcover edition.

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Product details

  • Hardcover: 832 pages
  • Publisher: W.H. Freeman & Company; 10 edition (24 Dec 2010)
  • Language: English
  • ISBN-10: 1429229438
  • ISBN-13: 978-1429229432
  • Product Dimensions: 27.7 x 21.6 x 3 cm
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (3 customer reviews)
  • See Complete Table of Contents

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Most Helpful Customer Reviews

4 of 4 people found the following review helpful By TomH211 on 21 Jan 2012
Format: Hardcover
The content is well thought out and displayed and is not written complicatedly even though it conveys some very complex ideas.

An absolutely fantastic textbook which I have found no faults with (something that I have never experience before).
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3 of 3 people found the following review helpful By flickstar on 21 Sep 2012
Format: Hardcover Verified Purchase
I usually take ages to read books on genetics, but not this one, I loved it. This book made the genetics easy to read and understand, would recommend!
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By A. A. Suleman on 31 Mar 2014
Format: Hardcover Verified Purchase
A brilliant source for beginners or those that are Ph.D. holders, like me, and forgotten some of the basics and details from the undergrad' years.
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Most Helpful Customer Reviews on Amazon.com (beta)

Amazon.com: 29 reviews
58 of 71 people found the following review helpful
riddled with run ons and ambiguity 8 April 2011
By Yuna - Published on Amazon.com
Format: Hardcover Verified Purchase
I'm on my first week of class and this is a bad sign of things to come. I am a studious student - an avid textbook reader. Learning has generally been a meditative, pleasurable act for me. Not so with this book! I should have taken a hint when the instructor told us that the most requested tool from their previous students was a reading guide. It's not that these college upperclassmen can't read, this book is really THAT poorly written. Let me demonstrate:

"Another way of characterizing and tracking a segment of DNA is to use a restriction fragment length polymorphism (RFLP). In Chapter 1, we learned that restriction enzymes are bacterial enzymes that cut DNA at specific base sequences in the genome (really? I don't remember reading about restriction enzymes and I've read chapter 1 twice. Why not just tell me what it is rather than make me feel like an idiot?). The target sequences have no biological significance in organisms other than bacteria; they are present purely by chance (I am not sure what the author is pondering here). Although the target sites are generally found consistently at specific locations, sometimes, on any one chromosome, a specific target site is missing or there is an extra site (wait wait, what happened to restriction fragment length polymorphism? are you going to explain that?). If such a site flanks the sequence hybridized by a probe, then a Southern hybridization (did not talk about "southern hybridization" before, only "southern blot") will reveal an RFLP (what site? the site that could be cut out by restriction enzyme?). Consider this simple (this word makes me feel dumb) example in which one chromosome of one parent contains an extra site not found in the other chromosomes of that type in that cross: [inserting confusing looking diagram here]"

If you understood that, good for you. For me, it's like trying to pitch a tent on a small cliff amidst a thunderstorm while warding off fire ants. I don't recommend it.
9 of 9 people found the following review helpful
By Skither211 - Published on Amazon.com
Format: Hardcover Verified Purchase
Beware. While it is not mentioned in the product title, nor the product description, and only in 1 or 2 of the sellers' condition notes, you are viewing an international edition. Look closely at the photo (you will have to zoom in). This book has different problem sets than the US edition.
12 of 14 people found the following review helpful
Why don't you keep simple writing... 26 July 2012
By periver - Published on Amazon.com
Format: Hardcover
Well like everybody I have read several science books, but this book is written not for students or people that just want to learn out of the book. Maybe is written for people that already know the subject because from the begining of each chapter you hate to continue to the second page.Your curiosity gets shutdown !.Take for example chapter 17 "Large scale Chromosomal Changes" After the first three pages you lost all interest. But wait... I also have Pierce's book "Genetics: a conceptual approach" Third edition (a bargain for 10.00 dollars) and chapter 9 is "Chromosone variation" ( about the same subject)I started reading the first page and I couldn't stop. It is well organized and simple words and excellent explained examples. The school requires switching books every semester beteen those two this fall semester is Griffiths time. I am glad I have Pierce, Brooker and Hartwell books with me to give a hand. I hope the authors evaluate their presentation of the book.
11 of 13 people found the following review helpful
Terrible Wording 1 Jun 2012
By jj2745 - Published on Amazon.com
Format: Hardcover
I have only gotten 3 chapters in, and I hope that things change, but this book is tedious to read. I also am an avid reader, and have taken MANY classes and read many books, and this is by far the most poorly written. They take SIMPLE concepts that have probably been learned in Bio 1 or 2 and make them seem complicated. I find myself starting to read and thinking I know what it is about to explain and then being taken aback, because only after reading 3 times over do I realize it is actually saying what I thought, but in the most wordy, confusing manner possible. AWFUL book.
4 of 4 people found the following review helpful
good classical genetics, poor treatment of modern genetics and technology 9 Dec 2013
By CMelnychuk - Published on Amazon.com
Format: Hardcover Verified Purchase
I would give this book a 2.5 if I could, as it is perfectly mediocre. Explanations are mostly adequate for a somewhat in-depth understanding in most topics. The first several chapters dealing with classical genetics (Mendelian topics, mapping, linkage, DNA replication, translation and transcription, some proteomics topics, gene regulation) are for the most part well done. This is essentially chapters 1-9, 13. The figures are very helpful and the text is written clearly (in general). There are, however, a few instances where the authors have omitted crucial information (presumably for the sake of simplification) irresponsibly. This becomes a glaring problem later in the book.

When it came to more modern genetic techniques and topics (genetic engineering, genomics, DNA repair), there were several instances when my professor had to tell us that the book was too simplified or misleading and to simply ignore it for our particular topic. The chapter on DNA repair was particularly troublesome. For example, there is one mechanism that, while described in detail, is completely incorrect. For the most part, however, the book simply leaves out many details or, in the case of DNA technology, describes genetic techniques that have not been used since the 80's. The sections dealing with making libraries, for example, include descriptions of phage and fosmid libraries. NOBODY uses these anymore. The descriptions of BACs, YACs, and other vectors that are actually used are on the simple side. Those older techniques aren't any simpler than modern techniques either, so why they are discussed is a mystery to me. It is at this point in the text (modern genetics) that the quality of the figures takes a dive. The practice of omitting information (presumably for simplification) now reduces some figures to colorful pictures of limited assistance.

As my class was more focused on molecular genetics, I can't comment on any of the sections dealing with population genetics.

So, I suppose it depends on what the focus of your class is, and how rigorously your instructor treats the material. If yours is an intro course focused on classical genetics, this book should be great for the most part. You are, however, left with a long and expensive book with only some decent content. If your course spends more time on modern genetics and/or delves deeper into some topics, then this book may only be of limited assistance. If you're in that group, however, your instructor is probably well aware of the deficiencies in the text and will structure the class accordingly.
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