I bought these because I wanted something to give me the closest possible experience to barefoot running, but with protection from the dirt and debris on the London streets. The Evoskins definitely do that job - the sensation is pretty close to barefoot, and they keep your feet clean and protect against injuries from broken glass, etc.
However, these shoes are not built to last. I would guess I've run no more than 50 miles in them, and already the soles are worn and splitting. The 'fingerprint' style tread started to wear off after just a couple of short runs, and has now gone completely.
The fit of these shoes isn't great. I find my little toes tend to pop out of their compartments when cornering, and generally my feet start sliding around uncomfortably inside the shoes as they get sweaty after a couple of miles.
I would recommend the Evoskins as a way to try out barefoot-style running over short distances, and for occasional wear. But they're definitely not suitable to use as your main running shoes, unfortunately.
I really wanted to love these shoes, and I hope Inov-8 will find a way to make them more robust in future.