Significant chunks of this book are astonishingly, infuriatingly bad. The subtitle of the book proclaims "On the New Immortality". And some of the better parts of the book are vignettes of Appleyard's meetings with various life extensionists, transhumanists, and immortalists. However, much of what Appleyard says is tired or unimaginative extensions of dreary OLD arguments about issues of life extension and life expansion. If only Appleyard had spent more time listening to what the "new immortalists" actually say - people like Nick Bostrom, Eliezer Yudkowsky, Max More, Audrey de Grey, and James Hughes - he would have found compelling answers to the arguments he raises.
For example, life might get boring, he says, if it went on for centuries whilst our mental capabilities remained much the same. Well, d'oh! transhumanists talk convincingly about expanding our mental capabilities and our interests in life - not just extending them. And aspects of the meaning of the human race would be changed if there was less certainty about death. Art would lose some of its current meaning, etc. Well, d'oh! why does that mean that we should continue to be enthralled by death, and prefer the currently limited and tragic human condition, to the much greater condition that humanity has the potential to transform into?
On the very last page, there's another of the (sadly) very many non-sequitors that Appleyward makes. He talks of a new world of "unageing, undying, unloving people". Hello?! Why on earth should "unageing and undying" imply "unloving"? This is nonsense.
The more interesting question is why an obviously bright person, like Appleyard, gets his thinking so immired and befuddled by these deathist (pro-death) principles? I believe the reason can be discerned from the unwarranted amount of time the book spends on trying to champion antiquated Catholic thinkers like Aquinas as (to quote) "most persuasive". Why, given the rich possible pickings from the highly creative transhumanist thinkers, does Appleyard instead tediously regurgitate tired old analyses about long-irrelevant theological debates? (He doesn't include the one about "how many angels could dance on a pinpoint?" but much of what he covers has a similar streak of other-worldiness.) In short, this is yet another example of the crippling effect that a life-long involvement in relgious thinking can have on someone's ability to reason clearly.
For a MUCH better treatment of the same concepts, go directly to the writings of the "new immortalists" themselves!