Indeed, this well-organized and thoroughly illustrated 16th edition of "Harrison's Principles of Internal Medicine" provides authoritative information on both medicine and surgery. Its contents show a true reflection of the experience, as well as the extensive individual knowledge of its numerous authors and/or contributors.
This edition not only guaranteed one of the most comprehensive coverage of every aspect of health and medicine, but offers many case-study insights, self-assessment questions (and answers), and diagnostically useful image databank. It also introduced many full color algorithms: in the form of additional scans, charts, and tables. Several chapters and sub-sections did receive remarkable updates: in particular are those dealing with infectious diseases, critical care, cardiology, oncology, and orthopaedics.
Also, the purchase of this book entitles the owner to a free online access to all the latest updates and materials, which became available only after the book has been printed. This free online access is said to remain valid until a newer edition of the book is published. That should be around 2009: which is some four years from the time of this review. The online access code is on a piece of paper embedded inside the book. Be sure not to misplace it!
There is quite a lot of things going for this 2607-paged book that I may end-up writing several pages in an attempt to highlight them all. Still, be assured that its depth of clinical information is simply voracious. But despite this, I do not honestly believe that anyone, (especially a student), who has already acquired the 15th edition need to spend again on this one. The information in the 15th edition is still very useful, as well as being current enough. In fact, anyone who cares to check will notice that the 'older' 15th edition has some twenty-two more pages than this 'newer' 16th edition. And in spite of being a few years older, its educational strength favorably matches those of this one. So, sticking with the 15th-ed until the next edition comes out is what I would suggest. This same suggestion applies to anyone who owns or uses either Kelley's or Cecil Textbook of Medicine, which is not more than five years old. But for all first-time buyers, who are considering this one, I will gladly advise you to proceed with the purchase. It is an investment, which is worth its weight in gold!