Ghostwritten is a series of short stories, each told in the first person by a different narrator, all of different nationalities, linked by chance encounters and cross-referencing. It's a very clever conceit, and the final couple of chapters contain enough references to the previous 7 or 8 to almost persuade you that it all adds up to a coherent narrative. Unfortunately, for me, it didn't quite.
I had two main problems with the book. The main one was, I just didn't believe in all the different characters. Partly this is the problem with a self-consciously "literary" work of fiction - it strives for literary effect. Many of the characters write literary similes and metaphors that were not only similar in style, but also seemed way out of character. ("I lay entombed in a slab of rock, in an embryo curl". ""Oy!" I yelled, and some genteel ladies walking dogs harrumphed. "Alfred Kopf!" I yelled, and a man dropped out of a tree with a turfy thump." Does anyone write, let alone speak like that in real life?) Plus the characters are mostly pretty unpleasant, making it hard to identify with their various troubles.
The other problem was the way the book occasionally lapses into cliche. The section in Ireland is horribly, horribly cliched, with everyone straight out of central casting, including the shop where you leave the money when the shopkeepers are absent, the ex-hippy who stayed and now grows locally respected marijuana, Father Wally the ubiquitous twinkle-eyed priest on his tricycle and, God help us, all-night sessions at the pub: "'Come by then later, Mo, or whenever, so. Eamonn O'Driscoll's boy is back with his accordion, and Father Wally's organising a lock-in.' Lock-ins at The Green Man. I was home.") And I wished he'd drawn the Americans with the same care he applied to the Japanese or Chinese - the military in particular seem to be based on characters from The Simpsons or Dr Strangelove.
As others have said, the old woman on Holy Mountain section was outstanding, worth reading the book for that alone, and the disembodied spirit was also beautifully handled. The St Petersburg gangsters were pretty unconvincing, though, and unlike the Asian chapters, felt like things he's got from movies than actually experienced.
So, ultimately, I felt it was clever, a very interesting read - but a bit cold, and more like an intellectual exercise than a depiction of real people with real problems - except for that wonderful old woman on the mountain...