A Genetic Switch, Third Edition, Phage Lambda Revisited
and over one million other books are available for Amazon Kindle .
Learn more
| ||||||||||||||||||||
 Trade In this Item for up to £11.85
Get an extra £5 when you trade in books worth £10 or more until June 30, 2012. Trade in A Genetic Switch: Phage Lambda Revisited for an Amazon.co.uk gift card of up to £11.85, which you can then spend on millions of items across the site. Trade-in values may vary (terms apply). Find more products eligible for trade-in.
|
Frequently Bought Together
Product details
|
More About the Author
Product Description
Review
Ptashne's clear and concise articulation of the essential scientific and experimental issues makes the book an ideal introductory text for the increasing number of interdisciplinary scientists moving into systems biology. More importantly, the detailed studies (summarized in these chapters) that relate properties of the molecular components to the function of the switch establish a high standard for the systems biology of more complex organisms. Science The clarity and care of 'A Genetic Switch' and its organization is a paradigm for communicating the structure and behavior of complex regulatory systems such as lambda. Periodic update of a book like this is important as a reminder of the level of our understanding of a system, in this case lambda, and of how we achieved that understanding. 'A Genetic Switch' is wonderful for what it is-a beautiful, concise (only 154 pages) exposition of the major molecular processes involved in lambda's lysis-lysogeny and induction decisions...The 3rd edition of 'A Genetic Switch' prompts us to remember the power of this under-utilized model system in discovering general principles of cellular function and behavior. Switch back!” Current Biology I enjoyed the book and have no major quibbles. The author has a talent for simplifying (but not oversimplifying) complicated ideas, he describes the theory and its experimental basis in a straightforward and plainspoken way, and he illustrates his points with drawings that contain just the right amount of detail. Connoisseurs will appreciate the new chapter on recent developments, in which some parts of the original picture are redrawn and others filled in... I strongly recommend the new edition of A Genetic Switch to students of molecular biology from the advanced undergraduate level up. The author and publisher are to be commended for supplying this volume at such a reasonable price. The Quarterly Review of Biology
Product Description
The first edition of Mark Ptashne's 1986 book describing the principles of gene regulation in phage lambda became a classic in both content and form, setting a standard of clarity and precise prose that has rarely been bettered. This edition is a reprint of the original text, together with a new chapter updating the story to 2004. Among the striking new developments are recent findings on long-range interactions between proteins bound to widely separated sites on the phage genome, and a detailed description of how gene activation works.
Inside This Book
(Learn More)
First Sentence
The genes of phage constitute a single DNA molecule-its chromosome-wrapped in a protein coat (Figure 1.1). Read the first page
Front Cover | Copyright | Table of Contents | Excerpt | Index | Back Cover
The genes of phage constitute a single DNA molecule-its chromosome-wrapped in a protein coat (Figure 1.1). Read the first page
Explore More
Concordance
Browse Sample PagesConcordance
Front Cover | Copyright | Table of Contents | Excerpt | Index | Back Cover
Tag this product(What's this?)Think of a tag as a keyword or label you consider is strongly related to this product.
Tags will help all customers organise and find favourite items. |
What Other Items Do Customers Buy After Viewing This Item?
Customer Reviews
There are no customer reviews yet on Amazon.co.uk.
5 star
4 star
3 star
2 star
1 star
Most Helpful Customer Reviews on Amazon.com (beta)
Amazon.com:
3 reviews
7 of 7 people found the following review helpful
a classic of scientific exposition
18 Aug 2005
Format:Paperback
I found out about this unassuming little book in Sean Carroll's
"Endless forms most beautiful" and was delighted. When I first started reading it, a stranger who saw me with it smiled and I soon found out why. It can be read by anyone with a modest scientific education (little more than high school) but it takes you up to the frontiers of research on gene regulation. Readers who remember the way "Scientific American" used to cover molecular biology in 1960's through the '80's (or have read reprints from that era) will appreciate the highly visual style and the clear prose. The genetic switch
in question determines whether the genes of a virus that infects a bacterial cell will quietly integrate themselves into the bacterial genome and be copied along with the bacteria's genes each time the cell divides or use the cell's machinery to make many copies of itself, quickly destroying the cell in the process. If you are like me you'll be fascinated to learn how this switch works and about the experiments that revealed its secrets.
"Endless forms most beautiful" and was delighted. When I first started reading it, a stranger who saw me with it smiled and I soon found out why. It can be read by anyone with a modest scientific education (little more than high school) but it takes you up to the frontiers of research on gene regulation. Readers who remember the way "Scientific American" used to cover molecular biology in 1960's through the '80's (or have read reprints from that era) will appreciate the highly visual style and the clear prose. The genetic switch
in question determines whether the genes of a virus that infects a bacterial cell will quietly integrate themselves into the bacterial genome and be copied along with the bacteria's genes each time the cell divides or use the cell's machinery to make many copies of itself, quickly destroying the cell in the process. If you are like me you'll be fascinated to learn how this switch works and about the experiments that revealed its secrets.
Easy to understand, detailed, and full of figures...
21 Nov 2011
Format:Paperback|Amazon Verified Purchase
Excellent title that sheds some light on how life, or not-life like viruses, works. You can read this book even if you are not a biologist, or if you have almost no scientific background. True, you might need to resort sometimes to Wikipedia in the later case, but you will likely gain something.
A classic book on bacterial gene regulation
26 Mar 2010
Format:Paperback|Amazon Verified Purchase
"A Genetic Switch" by Mark Ptashne is a modern classic of science writing. This book details the mechanism and presents the supporting data for the paradigm of bacterial gene regulation, the bacteriophage lambda repressor. What sets this book apart is not just the subject matter, but the clarity of Ptashne's writing and the superb illustrations that accompany his text. The combination of the two make the book useful for graduate students but also accessible for the general reader with an interest in science. Whenever new people join my laboratory, I have them read this book. Highly recommended.
Were these reviews helpful?
Let us know
Customer Discussions
|
This product's forum
Active discussions in related forums
Search Customer Discussions
|
Related forums
|
Listmania!
Look for similar items by category
- Books > Children's Books
- Books > Science & Nature > Biological Sciences > Biological Science > Molecular Biology
- Books > Science & Nature > Biological Sciences > Genetics
- Books > Science & Nature > Biological Sciences > Microbiology
- Books > Science & Nature > Popular Science > Genetics
- Books > Scientific, Technical & Medical
Look for similar items by subject
Feedback
- Would you like to update product info or give feedback on images?
- I am the Author, and I want to comment on my book.
- I am the Publisher, and I want to comment on this book.
|
